Atherosclerosis is a chronic inflammatory disease, in which the immune system has a
prominent role in its development and progression. Inflammation-induced endothelial …

It has long been observed that heart failure (HF) is associated with measures of systemic
inflammation. In recent years, there have been significant advancements in our …

Inflammation constitutes a complex, highly conserved cascade of molecular and cellular
events. Inflammation has been labeled as “the fire within,” is highly regulated, and is critical …

Background Emotional stress is associated with increased risk of cardiovascular disease.
We imaged the amygdala, a brain region involved in stress, to determine whether its resting …

Stress is a pervasive component of the human experience. While often considered an
adversity to be ignored, chronic stress has important pathological consequences, including …

Abstract Purpose of Review With the intention to summarize the currently available evidence
on the pathophysiological relevance of inflammation in heart failure, this review addresses …

As a greater proportion of patients survive their initial cardiac insult, medical systems
worldwide are being faced with an ever-growing need to understand the mechanisms …

Macrophages populate the healthy myocardium and, depending on their phenotype, may
contribute to tissue homeostasis or disease. Their origin and role in diastolic dysfunction, a …

Rationale: Macrophages reside in the healthy myocardium, participate in ischemic heart
disease, and modulate myocardial infarction (MI) healing. Their origin and roles in post-MI …

Posttraumatic stress disorder (PTSD) is characterized by a persistent maladaptive reaction
after exposure to severe psychological trauma. Traumatic events that may precipitate PTSD …