Alveolar epithelial type II cells as drivers of lung fibrosis in idiopathic pulmonary fibrosis
Alveolar epithelial type II cells (AT2) are a heterogeneous population that have critical
secretory and regenerative roles in the alveolus to maintain lung homeostasis. However …
secretory and regenerative roles in the alveolus to maintain lung homeostasis. However …
Mesenchymal stem cell‐based therapy of inflammatory lung diseases: current understanding and future perspectives
CR Harrell, R Sadikot, J Pascual… - Stem cells …, 2019 - Wiley Online Library
During acute or chronic lung injury, inappropriate immune response and/or aberrant repair
process causes irreversible damage in lung tissue and most usually results in the …
process causes irreversible damage in lung tissue and most usually results in the …
T cell apoptosis characterizes severe Covid-19 disease
S André, M Picard, R Cezar, F Roux-Dalvai… - Cell Death & …, 2022 - nature.com
Severe SARS-CoV-2 infections are characterized by lymphopenia, but the mechanisms
involved are still elusive. Based on our knowledge of HIV pathophysiology, we hypothesized …
involved are still elusive. Based on our knowledge of HIV pathophysiology, we hypothesized …
Molecular and cellular mechanisms of pulmonary fibrosis
Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …
The role of substance P in inflammatory disease
TM O'Connor, J O'Connell, DI O'Brien… - Journal of cellular …, 2004 - Wiley Online Library
The diffuse neuroendocrine system consists of specialised endocrine cells and peptidergic
nerves and is present in all organs of the body. Substance P (SP) is secreted by nerves and …
nerves and is present in all organs of the body. Substance P (SP) is secreted by nerves and …
Idiopathic pulmonary fibrosis: an epithelial/fibroblastic cross-talk disorder
Idiopathic pulmonary fibrosis is a chronic and usually progressive lung disorder of unknown
etiology. A growing body of evidence suggests that, in contrast to other interstitial lung …
etiology. A growing body of evidence suggests that, in contrast to other interstitial lung …
TIMP-1,-2,-3, and-4 in idiopathic pulmonary fibrosis. A prevailing nondegradative lung microenvironment?
Fibroblast proliferation and extracellular matrix accumulation characterize idiopathic
pulmonary fibrosis (IPF). We evaluated the presence of tissue inhibitor of metalloproteinase …
pulmonary fibrosis (IPF). We evaluated the presence of tissue inhibitor of metalloproteinase …
Evolving concepts of apoptosis in idiopathic pulmonary fibrosis
VJ Thannickal, JC Horowitz - Proceedings of the American Thoracic …, 2006 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is a chronic, relentlessly progressive fibrosing disease of
the lung of unknown etiology. Significant progress has been made in recent years in …
the lung of unknown etiology. Significant progress has been made in recent years in …
[HTML][HTML] Early growth response gene 1–mediated apoptosis is essential for transforming growth factor β1–induced pulmonary fibrosis
CG Lee, SJ Cho, MJ Kang, SP Chapoval… - The Journal of …, 2004 - ncbi.nlm.nih.gov
Fibrosis and apoptosis are juxtaposed in pulmonary disorders such as asthma and the
interstitial diseases, and transforming growth factor (TGF)-β 1 has been implicated in the …
interstitial diseases, and transforming growth factor (TGF)-β 1 has been implicated in the …
Mechanisms of N-acetylcysteine in the prevention of DNA damage and cancer, with special reference to smoking-related end-points
S De Flora, A Izzotti, F D'Agostini… - …, 2001 - academic.oup.com
Although smoking cessation is the primary goal for the control of cancer and other smoking-
related diseases, chemoprevention provides a complementary approach applicable to high …
related diseases, chemoprevention provides a complementary approach applicable to high …