Alveolar epithelial type II cells (AT2) are a heterogeneous population that have critical
secretory and regenerative roles in the alveolus to maintain lung homeostasis. However …

During acute or chronic lung injury, inappropriate immune response and/or aberrant repair
process causes irreversible damage in lung tissue and most usually results in the …

Severe SARS-CoV-2 infections are characterized by lymphopenia, but the mechanisms
involved are still elusive. Based on our knowledge of HIV pathophysiology, we hypothesized …

Pulmonary fibrosis is a chronic lung disease characterized by excessive accumulation of
extracellular matrix (ECM) and remodeling of the lung architecture. Idiopathic pulmonary …

The diffuse neuroendocrine system consists of specialised endocrine cells and peptidergic
nerves and is present in all organs of the body. Substance P (SP) is secreted by nerves and …

Idiopathic pulmonary fibrosis is a chronic and usually progressive lung disorder of unknown
etiology. A growing body of evidence suggests that, in contrast to other interstitial lung …

Fibroblast proliferation and extracellular matrix accumulation characterize idiopathic
pulmonary fibrosis (IPF). We evaluated the presence of tissue inhibitor of metalloproteinase …

Idiopathic pulmonary fibrosis (IPF) is a chronic, relentlessly progressive fibrosing disease of
the lung of unknown etiology. Significant progress has been made in recent years in …

Fibrosis and apoptosis are juxtaposed in pulmonary disorders such as asthma and the
interstitial diseases, and transforming growth factor (TGF)-β 1 has been implicated in the …

Although smoking cessation is the primary goal for the control of cancer and other smoking-
related diseases, chemoprevention provides a complementary approach applicable to high …