Background: An ENDO-European Reference Network (ERN) initiative was launched that
was endorsed by the European Society for Pediatric Endocrinology and the European …

Context: Central hypothyroidism (CH) is a particular hypothyroid condition due to an
insufficient stimulation by TSH of an otherwise normal thyroid gland. This condition raises …

Congenital hypothyroidism (CH) may be primary, due to a defect affecting the thyroid gland
itself, or central, due to impaired thyroid-stimulating hormone (TSH)-mediated stimulation of …

Central hypothyroidism is a rare and heterogeneous disorder that is characterized by a
defect in thyroid hormone secretion in an otherwise normal thyroid gland due to insufficient …

Central congenital hypothyroidism (CH) is defined as thyroid hormone (TH) deficiency at
birth due to insufficient stimulation by the pituitary of the thyroid gland. The incidence of …

Congenital hypothyroidism is the most frequent endocrine disorder in neonates. Controversy
exists regarding the necessity to adjust current screening programs to also diagnose …

Context: In our neonatal program, a number of infants with congenital hypothyroidism (CH)
had escaped diagnosis, when a spot RIA-TSH value of 20 mU/liter whole blood was used as …

Early detection of many disorders, mainly inherited, is feasible with population-wide analysis
of newborn dried blood spot samples. Phenylketonuria was the prototype disorder for …

Obesity is an escalating epidemic, but an effective noninvasive therapy is still scarce. For
obesity treatment, anorexigenic neuropeptides are promising tools, but their delivery from …

Hypothyroidism is divided in primary, caused by failure of thyroid function and secondary
(central) due to the failure of adequate thyroid-stimulating hormone (TSH) secretion from the …