Organic supramolecular aggregates based on water‐soluble cyclodextrins and calixarenes

Z Liu, X Dai, Y Sun, Y Liu - Aggregate, 2020 - Wiley Online Library
Macrocycle‐induced formation of pure organic supramolecular aggregates is a challenge
that has attracted considerable attention from researchers in the fields of chemistry, biology …

Development of calixarene-based drug nanocarriers

X Fan, X Guo - Journal of Molecular Liquids, 2021 - Elsevier
Chemotherapy is widely used for cancer treatment. However, many chemotherapeutic drugs
are insoluble in water, and many show similar toxicities toward target cells and healthy cells …

Multivalent calixarene-based liposomes as platforms for gene and drug delivery

JA Lebrón, M López-López, CB García-Calderón… - Pharmaceutics, 2021 - mdpi.com
The formation of calixarene-based liposomes was investigated, and the characterization of
these nanostructures was carried out using several techniques. Four amphiphilic …

Calixarene-mediated host–guest interactions leading to supramolecular assemblies: visualization by microscopy

R Nag, CP Rao - Chemical Communications, 2022 - pubs.rsc.org
Host–guest chemistry, particularly of supramolecules, has been an intriguing topic for
researchers for a long time due to its multiplicative applications ranging from chemical to …

Calix [4] arene polyamine triazoles: synthesis, aggregation and DNA binding

V Burilov, E Makarov, D Mironova, E Sultanova… - International Journal of …, 2022 - mdpi.com
Artificial gene delivery systems are in great demand from both scientific and practical
biomedical points of view. In this paper, we present the synthesis of a new click chemistry …

Novel biotin-linked amphiphilic calix [4] arene-based supramolecular micelles as doxorubicin carriers for boosted anticancer activity

D Du, Y Liu, J Lan, X Hou, J Liu, Q Shi… - Chemical …, 2023 - pubs.rsc.org
Supramolecular carrier-mediated chemotherapy is a highly attractive strategy for targeted
drug delivery. In this study, four novel biotin-linked calix [4] arenes BPCA1-BPCA4 have …

Dynamic covalent macrocycles co-delivering genes and drugs against drug-resistant cancer

Y Lyu, X Wu, AC Papageorgiou, J Yang, X Wang… - Cell Reports Physical …, 2022 - cell.com
Polymeric carriers have dominated the development of delivering chemotherapeutic drugs
and genes against drug-resistant cancer. However, the biocompatibility, loading, and …

PEG-Modified tert-Octylcalix[8]arenes as Drug Delivery Nanocarriers of Silibinin

D Budurova, D Momekova, G Momekov, P Shestakova… - Pharmaceutics, 2021 - mdpi.com
The hepatoprotective properties of silibinin, as well its therapeutic potential as an anticancer
and chemo-preventive agent, have failed to progress towards clinical development and …

Synthesis, characterization, and computational study of aggregates from amphiphilic calix [6] arenes. Effect of encapsulation on degradation kinetics of curcumin

S Moffa, M Aschi, M Bazzoni, FC Bonati… - Journal of Molecular …, 2022 - Elsevier
The aggregation behaviour of two tris (N-phenylureido)-calixarene derivatives, bearing three
octyl chains at the lower rim and differing from each other for the absence or presence of …

Aggregation, Cytotoxicity and DNA Binding in a Series of Calix [4] arene Amphiphile Containing Aminotriazole Groups

D Mironova, E Makarov, I Bilyukova, K Akyol… - Pharmaceuticals, 2023 - mdpi.com
The present work focuses on the study of the aggregation and complexing properties of
calixarenes as potential DNA condensation agents for gene delivery. In the current study, 1 …