Stress, catecholaminergic system and cancer

O Krizanova, P Babula, K Pacak - Stress, 2016 - Taylor & Francis
Stress as a modern civilization factor significantly affects our lives. While acute stress might
have a positive effect on the organism, chronic stress is usually detrimental and might lead …

[HTML][HTML] What are the immune responses during the growth of Ehrlich's tumor in ascitic and solid form?

IB Feitosa, B Mori, CBG Teles, AG da Costa - Life Sciences, 2021 - Elsevier
Traditionally, Ehrlich's tumor is used in experimental oncology to investigate the therapeutic
capacity of different synthetic chemotherapeutic agents or to evaluate the antitumoral activity …

Cellular uptake, cytotoxicity and in-vivo evaluation of Tamoxifen citrate loaded niosomes

DS Shaker, MA Shaker, MS Hanafy - International journal of pharmaceutics, 2015 - Elsevier
One of the main challenges in Tamoxifen cancer therapy is achieving localized, efficient and
sustained delivery without harming normal healthy organs. This study focused on evaluating …

[HTML][HTML] Repurposing Drugs in Oncology (ReDO)—Propranolol as an anti-cancer agent

P Pantziarka, G Bouche, V Sukhatme… - …, 2016 - ncbi.nlm.nih.gov
Propranolol (PRO) is a well-known and widely used non-selective beta-adrenergic receptor
antagonist (beta-blocker), with a range of actions which are of interest in an oncological …

[HTML][HTML] The beta adrenergic receptor antagonist propranolol alters mitogenic and apoptotic signaling in late stage breast cancer

A Montoya, A Varela-Ramirez, E Dickerson… - Biomedical journal, 2019 - Elsevier
Background Substantial evidence supports the use of inexpensive β-AR antagonists (beta
blockers) against a variety of cancers, and the β-AR antagonist propranolol was recently …

Apical splenic nerve electrical stimulation discloses an anti-inflammatory pathway relying on adrenergic and nicotinic receptors in myeloid cells

M Guyot, T Simon, C Panzolini, F Ceppo… - Brain, behavior, and …, 2019 - Elsevier
The autonomic nervous system innervates all lymphoid tissues including the spleen
therefore providing a link between the central nervous system and the immune system. The …

Potential cardioprotective and anticancer effects of carvedilol either free or as loaded nanoparticles with or without doxorubicin in solid Ehrlich carcinoma-bearing …

A Zidan, AAEL Saadany, GM El Maghraby… - Toxicology and Applied …, 2023 - Elsevier
Aim The aim of this study was to investigate the potential cardioprotective and anti-cancer
effects of carvedilol (CAR) either free or as loaded nano-formulated with or without …

Downregulation of miR-382 by propranolol inhibits the progression of infantile hemangioma via the PTEN-mediated AKT/mTOR pathway

D Li, P Li, Z Guo, H Wang… - … journal of molecular …, 2017 - spandidos-publications.com
Approximately 10% of infantile hemangiomas (IHs) are the most common vascular tumors
affecting children and are characterized by rapid growth, and can have destructive …

[HTML][HTML] Antineoplastic effect of pectic polysaccharides from green sweet pepper (Capsicum annuum) on mammary tumor cells in vivo and in vitro

ER Adami, CR Corso, NM Turin-Oliveira… - Carbohydrate …, 2018 - Elsevier
The present study investigated the antineoplastic effects of pectic polysaccharides that were
extracted from green sweet pepper (Capsicum annuum [CAP]) in the Ehrlich carcinoma in …

Folic acid grafted mixed polymeric micelles as a targeted delivery strategy for tamoxifen citrate in treatment of breast cancer

M Nasr, F Hashem, M Teiama, N Tantawy… - Drug Delivery and …, 2024 - Springer
The objective of this study was to develop folic acid (FA) grafted mixed polymeric micelles
loaded with Tamoxifen citrate (TMXC) to enhance its antitumor activity in breast tissues. The …