[HTML][HTML] Tumor-associated macrophages in breast cancer: Innocent bystander or important player?
SQ Qiu, SJH Waaijer, MC Zwager, EGE de Vries… - Cancer treatment …, 2018 - Elsevier
Tumor-associated macrophages (TAMs) are important tumor-promoting cells in the breast
tumor microenvironment. Preclinically TAMs stimulate breast tumor progression, including …
tumor microenvironment. Preclinically TAMs stimulate breast tumor progression, including …
Targeting arachidonic acid pathway by natural products for cancer prevention and therapy
Arachidonic acid (AA) pathway, a metabolic process, plays a key role in carcinogenesis.
Hence, AA pathway metabolic enzymes phospholipase A 2 s (PLA 2 s), cyclooxygenases …
Hence, AA pathway metabolic enzymes phospholipase A 2 s (PLA 2 s), cyclooxygenases …
Targeting the NFκB signaling pathways for breast cancer prevention and therapy
The activation of nuclear factor-kappaB (NFΚB), a proinflammatory transcription factor, is a
commonly observed phenomenon in breast cancer. It facilitates the development of a …
commonly observed phenomenon in breast cancer. It facilitates the development of a …
Breast cancer: major risk factors and recent developments in treatment
W Majeed, B Aslam, I Javed, T Khaliq… - Asian Pacific Journal …, 2014 - koreascience.kr
Breast cancer is the most common in women worldwide, with some 5-10% of all cases due
to inherited mutations of BRCA1 and BRCA2 genes. Obesity, hormone therapy and use of …
to inherited mutations of BRCA1 and BRCA2 genes. Obesity, hormone therapy and use of …
Celecoxib in cancer therapy and prevention–review
N Tołoczko-Iwaniuk… - Current Drug …, 2019 - ingentaconnect.com
Background and Objectives: It is generally accepted that inflammatory cells found in the
tumor microenvironment are involved in the neoplastic process, promoting cell proliferation …
tumor microenvironment are involved in the neoplastic process, promoting cell proliferation …
[HTML][HTML] Tumor‑associated macrophages in lung cancer: Friend or foe?
F Xu, Y Wei, Z Tang, B Liu… - Molecular Medicine …, 2020 - spandidos-publications.com
Typically, tumor‑associated macrophages (TAMs), an abundant population of leukocytes in
lung cancer, are affected by tumor microenvironment (TME) and shift towards either a pro …
lung cancer, are affected by tumor microenvironment (TME) and shift towards either a pro …
Berberine inhibits NLRP3 Inflammasome pathway in human triple-negative breast cancer MDA-MB-231 cell
M Yao, X Fan, B Yuan, N Takagi, S Liu, X Han… - … and Alternative Medicine, 2019 - Springer
Background Breast cancer is still the most common malignant tumor that threatens the
female's life in the world, especially triple-negative breast cancer (TNBC), one of the most …
female's life in the world, especially triple-negative breast cancer (TNBC), one of the most …
Molecular mechanism of anti-cancer activity of phycocyanin in triple-negative breast cancer cells
M Ravi, S Tentu, G Baskar, S Rohan Prasad… - BMC cancer, 2015 - Springer
Background Triple-negative breast cancers represent an important clinical challenge, as
these cancers do not respond to conventional endocrine therapies or other available …
these cancers do not respond to conventional endocrine therapies or other available …
Repurposing of drugs as STAT3 inhibitors for cancer therapy
Drug repurposing is a valuable approach in delivering new cancer therapeutics rapidly into
the clinic. Existing safety and patient tolerability data for drugs already in clinical use …
the clinic. Existing safety and patient tolerability data for drugs already in clinical use …
COX-2 modulates mammary tumor progression in response to collagen density
K Esbona, D Inman, S Saha, J Jeffery, P Schedin… - Breast Cancer …, 2016 - Springer
Background High breast density is linked to an increased risk of breast cancer, and
correlates with changes in collagen. In a mouse model of mammary carcinoma in the context …
correlates with changes in collagen. In a mouse model of mammary carcinoma in the context …