Sex-specific epigenetic programming in renal fibrosis and inflammation

P Kumar, HL Brooks - American Journal of Physiology …, 2023 - journals.physiology.org
The growing prevalence of hypertension, heart disease, diabetes, and obesity along with an
aging population is leading to a higher incidence of renal diseases in society. Chronic …

[HTML][HTML] Neuroimmunoendocrine link between chronic kidney disease and olfactory deficits

R Corona, B Ordaz, L Robles-Osorio… - Frontiers in Integrative …, 2022 - frontiersin.org
Chronic kidney disease (CKD) is a multifactorial pathology that progressively leads to the
deterioration of metabolic functions and results from deficient glomerular filtration and …

[HTML][HTML] X-chromosome and kidney function: evidence from a multi-trait genetic analysis of 908,697 individuals reveals sex-specific and sex-differential findings in …

M Scholz, K Horn, J Pott, M Wuttke, A Kühnapfel… - Nature …, 2024 - nature.com
X-chromosomal genetic variants are understudied but can yield valuable insights into
sexually dimorphic human traits and diseases. We performed a sex-stratified cross-ancestry …

Renal hypoxic reperfusion injury-on-chip model for studying combinational vitamin therapy

AR Chethikkattuveli Salih, A Asif… - ACS Biomaterials …, 2022 - ACS Publications
Renal ischemic-reperfusion injury decreases the chances of long-term kidney graft survival
and may lead to the loss of a transplanted kidney. During organ excision, the cycle of warm …

[HTML][HTML] The lower limit of reference of urinary albumin/creatinine ratio and the risk of chronic kidney disease progression in patients with type 2 diabetes mellitus

WH Tang, WC Hung, CP Wang, CC Wu… - Frontiers in …, 2022 - frontiersin.org
A urine albumin/creatinine ratio (UACR)< 30 mg/g is considered to be normal, while
increased risk of incident hypertension and cardiovascular disease mortality in subjects with …

Low Testosterone Level and Risk of Adverse Clinical Events among Male Patients with Chronic Kidney Disease: A Systematic Review and Meta‐Analysis of Cohort …

L Li, H Ju, H Jin, H Chen, M Sun… - Journal of Healthcare …, 2022 - Wiley Online Library
The phenomenon of low testosterone level is extremely common in male patients with
chronic kidney diseases (CKDs). This meta‐analysis aimed to evaluate whether the low …

[HTML][HTML] Associations between sleep-disordered breathing and serum uric acid and their sex differences: the Nagahama Study

H Sunadome, K Murase, Y Tabara, T Matsumoto… - Nutrients, 2023 - mdpi.com
Sleep-disordered breathing (SDB) is often accompanied by noncommunicable diseases
(NCDs), including gout. However, the association between serum uric acid (sUA) levels and …

[HTML][HTML] Associations between female birth sex and risk of chronic kidney disease development among people with HIV in the USA: a longitudinal, multicentre, cohort …

BA Shelton, D Sawinski, PA MacLennan, W Lee… - …, 2022 - thelancet.com
Background Women represent a meaningful proportion of new HIV diagnoses, with Black
women comprising 58% of new diagnoses among women. As HIV infection also increases …

Sex and Gender Differences in Acute Kidney Injury

LM Curtis - Kidney360, 2023 - journals.lww.com
Sex differences in acute kidney injury (AKI) continue to be identified. Generally, women are
protected from AKI when compared to men. Much of the protection exhibited in women is …

[HTML][HTML] Sex differences in renal function: Participation of gonadal hormones and prolactin

A Franco-Acevedo, R Echavarria, Z Melo - Endocrines, 2021 - mdpi.com
Kidney pathophysiology is influenced by gender. Evidence suggests that kidney damage is
more severe in males than in females and that sexual hormones contribute to this. Elevated …