In recent years, tumor immunotherapy has made significant progress. However, tumor
immunotherapy, particularly immune checkpoint inhibitors (eg, PD-1/PD-L1 inhibitors) …

The remarkable capacity of immunotherapies to induce durable regression in some patients
with metastatic cancer relies heavily on T cell recognition of tumor-presented antigens. As …

T cells and natural killer (NK) cells have complementary roles in tumor immunity, and dual T
cell and NK cell attack thus offers opportunities to deepen the impact of immunotherapy …

Cancer immunotherapy works by stimulating and strengthening the body's anti-tumor
immune response to eliminate cancer cells. Over the past few decades, immunotherapy has …

Osteosarcoma, with poor survival after metastasis, is considered the most common primary
bone cancer in adolescents. Notwithstanding the efforts of researchers, its five-year survival …

Over the past several decades, mRNA vaccines have evolved from a theoretical concept to a
clinical reality. These vaccines offer several advantages over traditional vaccine techniques …

Upon entering the biological milieu, nanomedicines swiftly interact with the surrounding
tissue fluid, subsequently being enveloped by a dynamic interplay of biomacromolecules …

Strategies of improving vaccine targeting ability toward lymph nodes have been attracting
considerable interest in recent years, though there are remaining delivery barriers based on …

Abstract The “hotness” or “coldness” of the tumors are determined by the information of the
cancer cells themselves, tumor immune characteristics, tumor microenvironment, and …

RNA vaccines have demonstrated their ability to solve the issues posed by the COVID-19
pandemic. This success has led to the renaissance of research into mRNA and their …