Lactate is an end point of Warburg-type metabolism found in inflammatory macrophages.
Recently, lactate was shown to modify histones of lipopolysaccharide (LPS)–activated …

Migrasomes, enriched with signaling molecules such as chemokines, cytokines and
angiogenic factors, play a pivotal role in the spatially defined delivery of these molecules …

Summary T helper type 2 (Th2) cytokine-activated M2 macrophages contribute to
inflammation resolution and wound healing. This study shows that IL-4-primed …

Macrophages play a pivotal role in the innate immune response. While their most
characteristic function is phagocytosis, it is important not to solely characterize macrophages …

Macrophages are involved in several critical activities associated with tissue repair and
regeneration. Current approaches in regenerative medicine are focusing on leveraging the …

In the tumor microenvironment (TME), communication between cancer cells and tumor-
associated macrophages (TAMs) through secreted extracellular proteins promotes cancer …

Ethnopharmacological relevance Cough variant asthma (CVA) is a chronic inflammatory
disease characterized by cough as the main symptom. Suhuang antitussive capsule …

Pterostilbene (PTS), known for its diverse beneficial effects via Nuclear factor erythroid-2
related factor (Nrf2) activation, holds potential for Diabetic Foot Ulcer (DFU) treatment …

Phagocytosis is a key process in innate immunity and homeostasis. After particle uptake,
newly formed phagosomes mature by acquisition of endolysosomal enzymes. Macrophage …

The activation of NLRP3 inflammasome is a key factor for various inflammatory diseases.
Here, we provide experimental evidence supporting the regulatory role of sphingosine-1 …