Serotonin regulates many physiological processes including sleep, appetite, and mood.
Thus, serotonergic system is an important target in the treatment of psychiatric disorders …

The brain‐derived neurotrophic factor, BDNF, was discovered more than 30 years ago and,
like other members of the neurotrophin family, this neuropeptide is synthetized as a …

Being different multifactorial forms of psychopathology, aggression, depression and suicidal
behavior, which is considered to be violent aggression directed against the self, have …

Serotonin modulates several physiological and cognitive pathways throughout the human
body that affect emotions, memory, sleep, and thermal regulation. The complex nature of the …

The role of serotonin in major depressive disorder (MDD) is the focus of accumulating
clinical and preclinical research. The results of these studies reflect the complexity of …

Worldwide, the incidence of major depressive disorder (MDD) is increasing annually,
resulting in greater economic and social burdens. Moreover, the pathological mechanisms …

Depression has a multifactorial etiology that arises from environmental, psychological,
genetic, and biological factors. Environmental stress and genetic factors acting through …

Disruption of the microbiota–gut–brain axis results in a wide range of pathologies that are
affected, from the brain to the intestine. Gut hormones released by enteroendocrine cells to …

Selective serotonin reuptake inhibitors (SSRIs) are currently widely used in the field of the
neuromodulation not only because of their anti-depressive effects but also due to their ability …

Serotonin (5-HT) receptors are found throughout central and peripheral nervous systems,
mainly in brain regions involved in the neurobiology of anxiety and depression. 5-HT …