Ageing, an unanswered question in the medical field, is a multifactorial process that results
in a progressive functional decline in cells, tissues and organisms. Although it is impossible …

Introduction Obesity is a disorder characterized by a disproportionate increase in body
weight in relation to height, mainly due to the accumulation of fat, and is considered a …

Hayes' Principles and Methods of Toxicology has long been established as a reliable and
informative reference for the concepts, methodologies, and assessments integral to …

Metabolomics offers a revolutionary framework for phenotyping individuals at a molecular
level that is needed for new breakthroughs in cell biology and personalized medicine. 1− 3 …

Background and aims Bariatric surgery is increasingly performed worldwide to treat morbid
obesity and is also known as metabolic surgery to reflect its beneficial metabolic effects …

The emerging field of metabolomics, in which a large number of small-molecule metabolites
from body fluids or tissues are detected quantitatively in a single step, promises immense …

Colorectal carcinogenesis involves the overexpression of many immediate-early response
genes associated with growth and inflammation, which significantly alters downstream …

To perform metabonomics investigations, it is necessary to generate comprehensive
metabolite profiles for complex samples such as biofluids and tissue/tissue extracts …

Obesity is currently epidemic in many countries worldwide and is strongly related to diabetes
and cardiovascular disease. This study investigated the differences in metabolomic profiling …

In order to perform metabonomic investigations, it is necessary to generate comprehensive
“global” metabolite profiles from complex samples, such as biofluids and tissues/tissue …