Detection, processing and reinforcement of social cues: regulation by the oxytocin system

R Menon, ID Neumann - Nature Reviews Neuroscience, 2023 - nature.com
Many social behaviours are evolutionarily conserved and are essential for the healthy
development of an individual. The neuropeptide oxytocin (OXT) is crucial for the fine-tuned …

The peptide that binds: a systematic review of oxytocin and its prosocial effects in humans

K MacDonald, TM MacDonald - Harvard review of psychiatry, 2010 - journals.lww.com
Oxytocin is a neuropeptide involved in a wide variety of social behaviors in diverse species.
Recent research on its effects in humans has generated an arresting picture of its role in the …

Intranasal oxytocin treatment for social deficits and biomarkers of response in children with autism

KJ Parker, O Oztan, RA Libove… - Proceedings of the …, 2017 - National Acad Sciences
Autism spectrum disorder (ASD) is characterized by core social deficits. Prognosis is poor, in
part, because existing medications target only associated ASD features. Emerging evidence …

Heart rate variability in individuals with autism spectrum disorders: A meta-analysis

YC Cheng, YC Huang, WL Huang - Neuroscience & Biobehavioral …, 2020 - Elsevier
Heart rate variability (HRV) in individuals with autism spectrum disorders (ASD) has been
investigated in some studies but the procedures and results vary. We conducted a …

Exogenous and evoked oxytocin restores social behavior in the Cntnap2 mouse model of autism

O Peñagarikano, MT Lázaro, XH Lu, A Gordon… - Science translational …, 2015 - science.org
Mouse models of neuropsychiatric diseases provide a platform for mechanistic
understanding and development of new therapies. We previously demonstrated that …

The role of oxytocin in psychiatric disorders: a review of biological and therapeutic research findings

DM Cochran, D Fallon, M Hill… - Harvard review of …, 2013 - journals.lww.com
Identify the biological role of oxytocin in forming attachments. Evaluate the relationship
between various neuropsychiatric disorders and oxytocin. Identify clinical implications of …

Evaluation of enzyme immunoassay and radioimmunoassay methods for the measurement of plasma oxytocin

A Szeto, PM McCabe, DA Nation, BA Tabak… - Psychosomatic …, 2011 - journals.lww.com
Objective: There is increased interest in measuring peripheral oxytocin levels to better
understand the role of this peptide in mammalian behavior, physiology, and disease. The …

Plasma oxytocin concentrations and OXTR polymorphisms predict social impairments in children with and without autism spectrum disorder

KJ Parker, JP Garner, RA Libove… - Proceedings of the …, 2014 - National Acad Sciences
The neuropeptide oxytocin (OXT) and its receptor (OXTR) regulate social functioning in
animals and humans. Initial clinical research suggests that dysregulated plasma OXT …

Prosocial effects of oxytocin and clinical evidence for its therapeutic potential

N Striepens, KM Kendrick, W Maier… - Frontiers in …, 2011 - Elsevier
There has been unprecedented interest in the prosocial effects of the neuropeptide oxytocin
in humans over the last decade. A range of studies has demonstrated correlations between …

Oxytocin levels tend to be lower in autistic children: A meta-analysis of 31 studies

S John, AV Jaeggi - Autism, 2021 - journals.sagepub.com
The oxytocin system may be different in autistic people, which could explain some of the
deficits in social behavior and cognition associated with autism spectrum disorder. However …