β subunits of voltage-gated calcium channels

AC Dolphin - Journal of bioenergetics and biomembranes, 2003 - Springer
Calcium channel β subunits have marked effects on the trafficking and on several of the
biophysical properties of all high voltage activated calcium channels. In this article I shall …

Voltage-dependent calcium channels: from structure to function

F Hofmann, L Lacinova, N Klugbauer - Reviews of Physiology …, 2005 - Springer
Voltage-activated calcium channels regulate the intracellular calcium concentration and
contribute thereby to calcium signalling in numerous cell types. These channels are widely …

The increased trafficking of the calcium channel subunit α2δ-1 to presynaptic terminals in neuropathic pain is inhibited by the α2δ ligand pregabalin

CS Bauer, M Nieto-Rostro, W Rahman… - Journal of …, 2009 - Soc Neuroscience
Neuropathic pain results from damage to the peripheral sensory nervous system, which may
have a number of causes. The calcium channel subunit α2δ-1 is upregulated in dorsal root …

The metal-ion-dependent adhesion site in the Von Willebrand factor-A domain of α2δ subunits is key to trafficking voltage-gated Ca2+ channels

C Canti, M Nieto-Rostro, I Foucault… - Proceedings of the …, 2005 - National Acad Sciences
All auxiliary α2δ subunits of voltage-gated Ca2+ (CaV) channels contain an extracellular
Von Willebrand factor-A (VWA) domain that, in α2δ-1 and-2, has a perfect metal-ion …

[HTML][HTML] Calcium signaling and T-type calcium channels in cancer cell cycling

JT Taylor, XB Zeng, JE Pottle, K Lee… - World journal of …, 2008 - ncbi.nlm.nih.gov
Regulation of intracellular calcium is an important signaling mechanism for cell proliferation
in both normal and cancerous cells. In normal epithelial cells, free calcium concentration is …

α2δ-1 gene deletion affects somatosensory neuron function and delays mechanical hypersensitivity in response to peripheral nerve damage

R Patel, CS Bauer, M Nieto-Rostro… - Journal of …, 2013 - Soc Neuroscience
The α2δ-1 subunit of voltage-gated calcium channels is upregulated after sensory nerve
injury and is also the therapeutic target of gabapentinoid drugs. It is therefore likely to play a …

Plasma membrane expression of T-type calcium channel α1 subunits is modulated by high voltage-activated auxiliary subunits

SJ Dubel, C Altier, S Chaumont, P Lory… - Journal of Biological …, 2004 - ASBMB
It has been suggested that the auxiliary subunits of high voltage-activated (HVA) calcium
channels modulate T-type, low voltage-activated (LVA) calcium channels. Such a regulation …

Low-voltage-activated (“T-Type”) calcium channels in review

AMR Yunker, MW McEnery - Journal of bioenergetics and biomembranes, 2003 - Springer
The past 5 years has witnessed an advance in our understanding of alpha1G (Ca v 3.1),
alpha1H (Ca v 3.2), and alpha1l (Ca v 3.3), the pore-forming subunits of T-type or low …

[HTML][HTML] The effect of α2-δ and other accessory subunits on expression and properties of the calcium channel α1G

AC Dolphin, CN Wyatt, J Richards… - The Journal of …, 1999 - ncbi.nlm.nih.gov
The effect of α2-δ and other accessory subunits on expression and properties of the calcium
channel α1G - PMC Back to Top Skip to main content NIH NLM Logo Access keys NCBI …

Neuronal distribution and functional characterization of the calcium channel α2δ‐2 subunit

M Hobom, S Dai, E Marais, L Lacinova… - European Journal of …, 2000 - Wiley Online Library
The auxiliary calcium channel α2δ subunit comprises a family of three genes, α2δ‐1 to 3,
which are expressed in a tissue‐specific manner. α2δ‐2 mRNA is found in the heart, skeletal …