HIV reverse transcriptase (RT) inhibitors are the important components of highly active
antiretroviral therapies (HAARTs) for anti-HIV treatment and pre-exposure prophylaxis in …

Adverse drug reactions (ADRs) are one of the major causes of morbidity and mortality
worldwide. It is well-known that individual genetic make-up is one of the causative factors of …

Background Due to the high prevalence of resistance to NNRTI-based ART since 2018,
consolidated recommendations from the WHO have indicated dolutegravir as the preferred …

Background Increased access to antiretroviral therapy (ART) has resulted in rising levels of
pretreatment human immunodeficiency virus drug resistance (PDR). This is the first …

Dolutegravir HIV drug resistance (HIVDR) data from Africa remain sparse. We reviewed
HIVDR results of Malawians on dolutegravir-based antiretroviral therapy (November 2020 …

Dolutegravir (DTG) is now a component of preferred first-line antiretroviral therapy (ART)
worldwide. ADVANCE and NAMSAL were two landmark clinical trials conducted exclusively …

Effective antiretroviral therapy (ART) adherence strategies for HIV+ adolescents and young
adults (AYA) are needed to prevent HIV-related morbidity, mortality, and onward …

Background: The transition to dolutegravir-containing antiretroviral therapy (ART) in low-and
middle-income countries (LMICs) was complicated by an initial safety signal in May 2018 …

Background Pre-treatment HIV drug resistance (PDR) may result in increased risk of
virological failure and acquisition of new resistance mutations. With recently increasing ART …

Objectives We aimed to measure the prevalence of maternal HIV viral load (VL) non-
suppression and assess associated factors, to evaluate progress towards United Nations …