Circular RNAs: biogenesis, function and role in human diseases

J Greene, AM Baird, L Brady, M Lim… - Frontiers in molecular …, 2017 - frontiersin.org
Circular RNAs (circRNAs) are currently classed as non-coding RNA (ncRNA) that, unlike
linear RNAs, form covalently closed continuous loops and act as gene regulators in …

Biogenesis, functions and clinical significance of circRNAs in gastric cancer

C Shan, Y Zhang, X Hao, J Gao, X Chen, K Wang - Molecular cancer, 2019 - Springer
Gastric cancer (GC) is one of the most common malignant tumours in the world and has high
morbidity and mortality. Circular RNAs (circRNAs) are a class of non-coding RNAs with …

Loss of a mammalian circular RNA locus causes miRNA deregulation and affects brain function

M Piwecka, P Glažar, LR Hernandez-Miranda… - Science, 2017 - science.org
INTRODUCTION Recently, a special class of RNAs has excited researchers and triggered
hundreds of now-published studies. Known as circular RNAs (circRNAs), these RNAs are …

Epigenetic silencing of CDR1as drives IGF2BP3-mediated melanoma invasion and metastasis

D Hanniford, A Ulloa-Morales, A Karz… - Cancer cell, 2020 - cell.com
Metastasis is the primary cause of death of cancer patients. Dissecting mechanisms
governing metastatic spread may uncover important tumor biology and/or yield promising …

Circular RNA ciRS-7—a promising prognostic biomarker and a potential therapeutic target in colorectal cancer

W Weng, Q Wei, S Toden, K Yoshida, T Nagasaka… - Clinical Cancer …, 2017 - AACR
Purpose: Colorectal cancer is one of the most common malignancies worldwide. Recently, a
novel circular RNA, ciRS-7, was proposed to be a potential miR-7 sponge. As miR-7, a …

Circular RNAs in cancer: an emerging key player

Y Dong, D He, Z Peng, W Peng, W Shi, J Wang… - Journal of hematology & …, 2017 - Springer
Circular RNAs (circRNAs) are a class of endogendous RNAs that form a covalently closed
continuous loop and exist extensively in mammalian cells. Majority of circRNAs are …

Circular RNAs: biogenesis, function, and a role as possible cancer biomarkers

L Bolha, M Ravnik-Glavač… - International journal of …, 2017 - Wiley Online Library
Circular RNAs (circRNAs) are a class of noncoding RNAs (ncRNAs) that form covalently
closed continuous loop structures, lacking the terminal 5′ and 3′ ends. CircRNAs are …

[HTML][HTML] MicroRNA-486-5p and microRNA-486-3p: Multifaceted pleiotropic mediators in oncological and non-oncological conditions

AM ElKhouly, RA Youness, MZ Gad - Non-coding RNA research, 2020 - Elsevier
Despite historically known as “junk” DNA, nowadays non-coding RNA transcripts (ncRNAs)
are considered as fundamental players in various physiological and pathological conditions …

MiR-7 in cancer development

P Korać, M Antica, M Matulić - Biomedicines, 2021 - mdpi.com
MicroRNAs (miRNAs) are short non-coding RNA involved in the regulation of specific mRNA
translation. They participate in cellular signaling circuits and can act as oncogenes in tumor …

microRNA-7: a tumor suppressor miRNA with therapeutic potential

FC Kalinowski, RAM Brown, C Ganda, KM Giles… - The international journal …, 2014 - Elsevier
Abstract microRNAs are a family of endogenous, short, non-coding RNAs that play critical
roles in regulating gene expression for key cellular processes in normal and abnormal …