Drug-induced toxicity, which impairs human organ function, is a serious problem during drug
development that hinders the clinical use of many marketed drugs, and the underlying …

Severe cutaneous adverse reactions (SCARs), which include Stevens–Johnson syndrome
and toxic epidermal necrolysis, drug reaction with eosinophilia and systemic symptoms (also …

Importance Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are
severe drug reactions associated with a high rate of mortality and morbidity. There is no …

Background Supportive care is the cornerstone of management of adult and paediatric
Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN). However …

Abstract Stevens-Johnson Syndrome (SJS) is a severe and rare adverse drug reaction
associated with significant morbidity and mortality. Although SJS is commonly triggered by …

Delayed drug T-cell immune-mediated hypersensitivity reactions have a large clinical
heterogeneity varying from mild maculopapular exanthema (MPE) to severe cutaneous …

Abstract Background Stevens–Johnson syndrome (SJS) and toxic epidermal necrolysis
(TEN) are rare but potentially life‐threatening cutaneous adverse reactions. There is still no …

Toxic epidermal necrolysis, Leyll's syndrome (TEN), is a rare mucocutaneous blistering
disease burdened with high mortality rates. The diagnosis of TEN is based on clinical …

Stevens-Johnson syndrome and toxic epidermal necrolysis (SJS/TEN) is the most life-
threatening disease managed by dermatologists. Although SJS/TEN only affects 1 to 5 …

1 Has C, Bauer JW, Bodemer C et al. Consensus reclassification of inherited epidermolysis
bullosa and other disorders with skin fragility. Br J Dermatol 2020; 183: 614–27. 2 Hérissé …