Molecular Landscape of LncRNAs in Prostate Cancer: A focus on pathways and therapeutic targets for intervention

S Mirzaei, MDA Paskeh, E Okina, MH Gholami… - Journal of Experimental …, 2022 - Springer
Background One of the most malignant tumors in men is prostate cancer that is still incurable
due to its heterogenous and progressive natures. Genetic and epigenetic changes play …

Biomaterial‐based gene therapy

Y Yu, Y Gao, L He, B Fang, W Ge, P Yang, Y Ju… - MedComm, 2023 - Wiley Online Library
Gene therapy, a medical approach that involves the correction or replacement of defective
and abnormal genes, plays an essential role in the treatment of complex and refractory …

Lnc2Cancer 3.0: an updated resource for experimentally supported lncRNA/circRNA cancer associations and web tools based on RNA-seq and scRNA-seq data

Y Gao, S Shang, S Guo, X Li, H Zhou, H Liu… - Nucleic acids …, 2021 - academic.oup.com
Abstract An updated Lnc2Cancer 3.0 (http://www. bio-bigdata. net/lnc2cancer or http://bio-
bigdata. hrbmu. edu. cn/lnc2cancer) database, which includes comprehensive data on …

The roles of H19 in regulating inflammation and aging

B Wang, CW Suen, H Ma, Y Wang, L Kong… - Frontiers in …, 2020 - frontiersin.org
Accumulating evidence suggests that long non-coding RNA H19 correlates with several
aging processes. However, the role of H19 in aging remains unclear. Many studies have …

Exosome-transmitted miR-29a induces colorectal cancer metastasis by destroying the vascular endothelial barrier

K Liu, R Dou, C Yang, Z Di, D Shi, C Zhang… - …, 2023 - academic.oup.com
Metastasis is the leading cause of colorectal cancer treatment failure and mortality.
Communication between endothelium and tumor cells in the tumor microenvironment is …

Gp130-Mediated STAT3 Activation Contributes to the Aggressiveness of Pancreatic Cancer through H19 Long Non-Coding RNA Expression

N Sasaki, K Hirano, Y Shichi, F Gomi, H Yoshimura… - Cancers, 2022 - mdpi.com
Simple Summary The signal transducer and activator of transcription 3 (STAT3) activation
correlate with the aggressiveness of pancreatic ductal adenocarcinoma (PDAC). We …

Regulatory network of miRNA, lncRNA, transcription factor and target immune response genes in bovine mastitis

AR Tucker, NA Salazar, AO Ayoola, E Memili… - Scientific Reports, 2021 - nature.com
Pre-and post-transcriptional modifications of gene expression are emerging as foci of
disease studies, with some studies revealing the importance of non-coding transcripts, like …

The induction of ferroptosis by KLF11/NCOA4 axis: the inhibitory role in clear cell renal cell carcinoma

ZQ Zhou, X Lv, SB Liu, HC Qu, QP Xie, LF Sun, G Li - Human Cell, 2023 - Springer
Ferroptosis is a form of cell death and has great potential application in the treatment of
many cancers, including clear cell renal cell carcinoma (ccRCC). Herein, we identified the …

[HTML][HTML] Epigenetic mechanisms in vascular inflammation: modulation of endothelial adhesion molecules and endothelium-leukocyte adhesion

N Calabriso, M Massaro, E Scoditti… - Frontiers in Bioscience …, 2023 - imrpress.com
The endothelium, an essential component of the vascular system, plays a critical role in the
inflammatory response. Under pro-inflammatory stimuli, endothelial cells undergo activation …

A glycolysis-based long non-coding RNA signature accurately predicts prognosis in renal carcinoma patients

H Cao, H Tong, J Zhu, C Xie, Z Qin, T Li, X Liu… - Frontiers in …, 2021 - frontiersin.org
Background The prognosis of renal cell carcinoma (RCC) varies greatly among different risk
groups, and the traditional indicators have limited effect in the identification of risk grade in …