The problem of drug resistance due to long-term use of antibiotics has been a concern for
years. As this problem grows worse, infections caused by multiple bacteria are expanding …

The identification of the first mobile colistin resistance (MCR) gene, mcr-1, in 2015 triggered
a rash of mcr screening reports. Subsequently, nine MCR-family genes and their variants …

This AASLD Guidance provides a data-supported approach to the management of ascites
and HRS. It differs from the AASLD Guidelines, which are supported by systematic reviews …

The natural history of cirrhosis is characterised by an asymptomatic compensated phase
followed by a decompensated phase, marked by the development of overt clinical signs, the …

The British Society of Gastroenterology in collaboration with British Association for the Study
of the Liver has prepared this document. The aim of this guideline is to review and …

Background & Aims Liver transplantation (LT) has been proposed as an effective salvage
therapy even for the sickest patients with acute-on-chronic liver failure (ACLF). This large …

Progression of chronic liver disease is precipitated by hepatocyte loss, inflammation and
fibrosis. This process results in the loss of critical hepatic functions, increasing morbidity and …

Background & Aims Antibiotic resistance has been increasingly reported in patients with
decompensated cirrhosis in single-center studies. Prospective investigations reporting …

Bacterial infections are frequent in cirrhotic patients with acute decompensation or acute-on-
chronic liver failure and can complicate the clinical course. Delayed diagnosis and …

Infections in Patients with Cirrhosis Patients with cirrhosis are at increased risk for serious
infections, including spontaneous bacterial peritonitis, multidrug-resistant infection, and …