Epidemiology, diagnostics, and biomarkers of autoimmune neuromuscular junction disorders

AR Punga, P Maddison, JM Heckmann… - The Lancet …, 2022 - thelancet.com
Autoimmune neuromuscular junction disorders are rare. However, myasthenia gravis is
being increasingly recognised in people older than 50 years. In the past 5–10 years …

Serological and experimental studies in different forms of myasthenia gravis

A Vincent, S Huda, M Cao, H Cetin… - Annals of the New …, 2018 - Wiley Online Library
Antibodies to the acetylcholine receptor (AChR) have been recognized for over 40 years
and have been important in the diagnosis of myasthenia gravis (MG), and its recognition in …

Clinical value of cell-based assays in the characterisation of seronegative myasthenia gravis

V Damato, G Spagni, G Monte, M Woodhall… - Journal of Neurology …, 2022 - jnnp.bmj.com
Objective Patients with myasthenia gravis without acetylcholine receptor (AChR) or muscle-
specific kinase (MuSK) antibodies detected by radioimmunoprecipitation assays (RIAs) are …

COVID-19 vaccination and late-onset myasthenia gravis: a new case report and review of the literature

E Virgilio, G Tondo, C Montabone, C Comi - International Journal of …, 2022 - mdpi.com
Myasthenia gravis (MG) is a rare autoimmune disease that is potentially threatening for
patient life. Auto-antibodies targeting structures of the neuromuscular junction, particularly …

Clinical pitfalls and serological diagnostics of MuSK myasthenia gravis

YN Kwon, M Woodhall, JJ Sung, KK Kim, YM Lim… - Journal of …, 2023 - Springer
Background We aimed to evaluate the diagnostic accuracy of enzyme-linked
immunosorbent assay (ELISA) for anti-muscle specific tyrosine kinase (MuSK) antibody (Ab) …

Post-infectious autoimmunity in the central (CNS) and peripheral (PNS) nervous systems: an African perspective

AP Ndondo, B Eley, JM Wilmshurst… - Frontiers in …, 2022 - frontiersin.org
The direct impact and sequelae of infections in children and adults result in significant
morbidity and mortality especially when they involve the central (CNS) or peripheral nervous …

Myasthenic ophthalmoparesis: time to resolution after initiating immune therapies

TA Europa, M Nel, JM Heckmann - Muscle & Nerve, 2018 - Wiley Online Library
Introduction: Although immunotherapies such as prednisone are effective in treating
myasthenic muscle weakness, their effect on resolution of myasthenic‐induced persistent …

Improving laboratory diagnostics in myasthenia gravis

M Gastaldi, S Scaranzin, P Businaro… - Expert Review of …, 2021 - Taylor & Francis
Introduction: Myasthenia gravis (MG) is a prototypical autoimmune disease, characterized by
pathogenic autoantibodies targeting structures of the neuromuscular junction …

Juvenile myasthenia gravis in Norway: Clinical characteristics, treatment, and long-term outcome in a nationwide population-based cohort

TH Popperud, MI Boldingh, M Rasmussen… - european journal of …, 2017 - Elsevier
Background This study aimed to characterize juvenile myasthenia gravis in a national
population-based cohort in Norway, and to evaluate long-term outcome and potential …

The epidemiology and phenotypes of ocular manifestations in childhood and juvenile myasthenia gravis: a review

JM Heckmann, TA Europa, AJ Soni, M Nel - Frontiers in neurology, 2022 - frontiersin.org
Myasthenia gravis (MG) appears to have a similar incidence among adult populations
worldwide. However, epidemiological and phenotypic differences have been noted among …