Nonlinear and stochastic dynamics in the heart
In a normal human life span, the heart beats about 2–3 billion times. Under diseased
conditions, a heart may lose its normal rhythm and degenerate suddenly into much faster …
conditions, a heart may lose its normal rhythm and degenerate suddenly into much faster …
Cardiac alternans: from bedside to bench and back
Cardiac alternans arises from dynamical instabilities in the electrical and calcium cycling
systems of the heart, and often precedes ventricular arrhythmias and sudden cardiac death …
systems of the heart, and often precedes ventricular arrhythmias and sudden cardiac death …
Global, regional, and national age-sex-specific mortality and life expectancy, 1950–2017: a systematic analysis for the Global Burden of Disease Study 2017
D Dicker, G Nguyen, D Abate, KH Abate, SM Abay… - The lancet, 2018 - thelancet.com
Background Assessments of age-specific mortality and life expectancy have been done by
the UN Population Division, Department of Economics and Social Affairs (UNPOP), the …
the UN Population Division, Department of Economics and Social Affairs (UNPOP), the …
A rule‐based method to model myocardial fiber orientation in cardiac biventricular geometries with outflow tracts
R Doste, D Soto‐Iglesias, G Bernardino… - … journal for numerical …, 2019 - Wiley Online Library
Rule‐based methods are often used for assigning fiber orientation to cardiac anatomical
models. However, existing methods have been developed using data mostly from the left …
models. However, existing methods have been developed using data mostly from the left …
[HTML][HTML] Machine learning in drug development: Characterizing the effect of 30 drugs on the QT interval using Gaussian process regression, sensitivity analysis, and …
Prolonged QT intervals are a major risk factor for ventricular arrhythmias and a leading
cause of sudden cardiac death. Various drugs are known to trigger QT interval prolongation …
cause of sudden cardiac death. Various drugs are known to trigger QT interval prolongation …
Electrophysiological mechanisms underlying T-wave alternans and their role in arrhythmogenesis
T-wave alternans (TWA) reflects every-other-beat alterations in the morphology of the
electrocardiogram ST segment or T wave in the setting of a constant heart rate, hence, in the …
electrocardiogram ST segment or T wave in the setting of a constant heart rate, hence, in the …
A machine-learning approach for long-term prediction of experimental cardiac action potential time series using an autoencoder and echo state networks
Computational modeling and experimental/clinical prediction of the complex signals during
cardiac arrhythmias have the potential to lead to new approaches for prevention and …
cardiac arrhythmias have the potential to lead to new approaches for prevention and …
Computational modeling of non-linear diffusion in cardiac electrophysiology: A novel porous-medium approach
The electrophysiological behavior of excitable biological media has been traditionally
modeled using a nonlinear reaction–diffusion equation commonly known as the cable …
modeled using a nonlinear reaction–diffusion equation commonly known as the cable …
Experimental validation of a variational data assimilation procedure for estimating space-dependent cardiac conductivities
Customization of mathematical and numerical models to patient-specific settings is a critical
step of the translation process bringing scientific computing to the clinical activity. In …
step of the translation process bringing scientific computing to the clinical activity. In …
Long-time prediction of arrhythmic cardiac action potentials using recurrent neural networks and reservoir computing
The electrical signals triggering the heart's contraction are governed by non-linear
processes that can produce complex irregular activity, especially during or preceding the …
processes that can produce complex irregular activity, especially during or preceding the …