Chemotherapeutics occupy a pivotal role in the medication of different types of cancers, but
the prevalence and mortality rates of cancer remain high. The drug resistance and low …

Cancer is a large group of diseases that can affect any organ or body tissue due to the
abnormal cellular growth with the unknown reasons. Many of the existing chemotherapeutic …

Creating effective, ecologically friendly, and commercially viable synthetic routes is crucial in
the design and synthesis of organic substances. Quinazoline, a heterocyclic compound with …

Non-small cell lung cancer (NSCLC) is an obscure disease whose incidence is increasing
worldwide day by day, and PI3Kα is one of the major targets for cell proliferation due to the …

Cancer, a noncommunicable disease, is the leading cause of mortality worldwide and is
anticipated to rise by 75% in the next two decades, reaching approximately 25 million cases …

In this study, 16 new compounds were synthesized starting from methylparaben. These new
compounds consist of eight arylidenehydrazide derivatives and eight thiazolidin‐4‐on …

In the current study, series of 2-arylbenzimidazole-thiopyrimidine and-thioquinazolin-4 (3H)-
ones conjugates 12a-d, 13a, b and 14a-l have been synthesized. All the synthesized …

Cancer cells have the ability of dysregulation and autonomous proliferation due to
unchecked production of definite molecules. These molecules are involved in the cell growth …

Epidermal growth factor receptor (EGFR) enhances lung cancer development, due to their
inability to permeate the cell membrane, secreted growth factors work through specialized …

ABSTRACT “A journey of mixed emotions” is a quote that best describes the progress chart
of vascular endothelial growth factor receptor (VEGFR) inhibitors as cancer therapeutics in …