Bone tumors are a rare and heterogeneous group of neoplasms that occur in the bone. The
diversity and considerable morphologic overlap of bone tumors with other mesenchymal …

The historic term 'histiocytosis' meaning 'tissue cell'is used as a unifying concept for
diseases characterized by pathogenic myeloid cells that share histological features with …

SARS-CoV-2 causes profound changes in the sense of smell, including total smell loss.
Although these alterations are often transient, many patients with COVID-19 exhibit olfactory …

Immunotherapy is a mainstay of non-small cell lung cancer (NSCLC) management. While
tumor mutational burden (TMB) correlates with response to immunotherapy, little is known …

With the introduction of large-scale molecular profiling methods and high-throughput
sequencing technologies, the genomic features of most lymphoid neoplasms have been …

Langerhans cell histiocytosis (LCH) is caused by clonal expansion of myeloid precursors
that differentiate into CD1a+/CD207+ cells in lesions that leads to a spectrum of organ …

Histiocytic neoplasms are a heterogeneous group of clonal haematopoietic disorders that
are marked by diverse mutations in the mitogen-activated protein kinase (MAPK) pathway …

Dendritic cells (DCs) are a unique class of immune cells that act as a bridge between innate
and adaptive immunity. The discovery of DCs by Cohen and Steinman in 1973 laid the …

Neurodegenerative diseases (ND) are characterized by progressive loss of neuronal
function. Mechanisms of ND pathogenesis are incompletely understood, hampering the …

Histiocytic neoplasms are rare hematologic disorders accounting for less than 1% of cancers
of the soft tissue and lymph nodes. Clinical presentation and prognosis of these disorders …