ACE2 receptor polymorphism: Susceptibility to SARS-CoV-2, hypertension, multi-organ failure, and COVID-19 disease outcome
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has emerged in
Chinese people in December 2019 and has currently spread worldwide causing the COVID …
Chinese people in December 2019 and has currently spread worldwide causing the COVID …
Renin-angiotensin system blockers and the COVID-19 pandemic: at present there is no evidence to abandon renin-angiotensin system blockers
AHJ Danser, M Epstein, D Batlle - Hypertension, 2020 - Am Heart Assoc
During the spread of the severe acute respiratory syndrome coronavirus-2, some reports of
data still emerging and in need of full analysis indicate that certain groups of patients are at …
data still emerging and in need of full analysis indicate that certain groups of patients are at …
[HTML][HTML] Age-related morbidity and mortality among patients with COVID-19
SJ Kang, SI Jung - Infection & chemotherapy, 2020 - ncbi.nlm.nih.gov
Abstract On March 11, 2020, the World Health Organization declared coronavirus disease
(COVID-19), caused by the novel coronavirus severe acute respiratory syndrome …
(COVID-19), caused by the novel coronavirus severe acute respiratory syndrome …
The vasoprotective axes of the renin-angiotensin system: physiological relevance and therapeutic implications in cardiovascular, hypertensive and kidney diseases
XC Li, J Zhang, JL Zhuo - Pharmacological research, 2017 - Elsevier
The renin-angiotensin system (RAS) is undisputedly one of the most prominent endocrine
(tissue-to-tissue), paracrine (cell-to-cell) and intracrine (intracellular/nuclear) vasoactive …
(tissue-to-tissue), paracrine (cell-to-cell) and intracrine (intracellular/nuclear) vasoactive …
Downregulation of ACE2 induces overstimulation of the renin–angiotensin system in COVID-19: should we block the renin–angiotensin system?
F Silhol, G Sarlon, JC Deharo, B Vaïsse - Hypertension Research, 2020 - nature.com
Severe acute respiratory syndrome coronavirus 2 is the cause of the ongoing coronavirus
disease-19 (COVID-19) pandemic. Mortality is mainly due to acute respiratory distress …
disease-19 (COVID-19) pandemic. Mortality is mainly due to acute respiratory distress …
SARS-CoV-2 and cardiovascular complications: From molecular mechanisms to pharmaceutical management
L Wu, AM O'Kane, H Peng, Y Bi, D Motriuk-Smith… - Biochemical …, 2020 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19), elicited by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) infection, is a pandemic public health emergency of …
syndrome coronavirus 2 (SARS-CoV-2) infection, is a pandemic public health emergency of …
Effect of angiotensin-converting enzyme inhibition and angiotensin II receptor blockers on cardiac angiotensin-converting enzyme 2
CM Ferrario, J Jessup, MC Chappell, DB Averill… - Circulation, 2005 - Am Heart Assoc
Background—Angiotensin-converting enzyme 2 (ACE2) has emerged as a novel regulator
of cardiac function and arterial pressure by converting angiotensin II (Ang II) into the …
of cardiac function and arterial pressure by converting angiotensin II (Ang II) into the …
Hydrolysis of biological peptides by human angiotensin-converting enzyme-related carboxypeptidase
C Vickers, P Hales, V Kaushik, L Dick, J Gavin… - Journal of Biological …, 2002 - ASBMB
Human angiotensin-converting enzyme-related carboxypeptidase (ACE2) is a zinc
metalloprotease whose closest homolog is angiotensin I-converting enzyme. To begin to …
metalloprotease whose closest homolog is angiotensin I-converting enzyme. To begin to …
ACE2: from vasopeptidase to SARS virus receptor
AJ Turner, JA Hiscox, NM Hooper - Trends in pharmacological sciences, 2004 - cell.com
The zinc metallopeptidase angiotensin-converting enzyme 2 (ACE2) is the only known
human homologue of the key regulator of blood pressure angiotensin-converting enzyme …
human homologue of the key regulator of blood pressure angiotensin-converting enzyme …
Expression of ACE2, soluble ACE2, angiotensin I, angiotensin II and angiotensin-(1-7) is modulated in COVID-19 patients
The etiological agent of COVID-19 SARS-CoV-2, is primarily a pulmonary-tropic
coronavirus. Infection of alveolar pneumocytes by SARS-CoV-2 requires virus binding to the …
coronavirus. Infection of alveolar pneumocytes by SARS-CoV-2 requires virus binding to the …