Cell senescence and central regulators of immune response
SM Lunin, EG Novoselova, OV Glushkova… - International Journal of …, 2022 - mdpi.com
Pathways regulating cell senescence and cell cycle underlie many processes associated
with ageing and age-related pathologies, and they also mediate cellular responses to …
with ageing and age-related pathologies, and they also mediate cellular responses to …
Old and novel functions of caspase-2
MA Miles, T Kitevska-Ilioski, CJ Hawkins - International review of cell and …, 2017 - Elsevier
Although caspase-2 is a highly conserved protease that has received a lot of research
attention, consensus about its roles and the molecular mechanisms that underpin them has …
attention, consensus about its roles and the molecular mechanisms that underpin them has …
Antiapoptotic function of RNA‐binding protein HuR effected through prothymosin α
A Lal, T Kawai, X Yang, K Mazan‐Mamczarz… - The EMBO …, 2005 - embopress.org
We report the antiapoptotic effect of RNA‐binding protein HuR, a critical regulator of the post‐
transcriptional fate of target transcripts. Among the most prominent mRNAs complexing with …
transcriptional fate of target transcripts. Among the most prominent mRNAs complexing with …
PFOA-induced ovotoxicity differs between lean and obese mice with impacts on ovarian reproductive and DNA damage sensing and repair proteins
M Estefanía González-Alvarez, A Severin… - Toxicological …, 2022 - academic.oup.com
Perfluorooctanoic acid (PFOA) is an environmentally persistent perfluoroalkyl substance that
is widely used in consumer products. Exposure to PFOA is associated with reproductive and …
is widely used in consumer products. Exposure to PFOA is associated with reproductive and …
The Histone Chaperones SET/TAF‐1β and NPM1 Exhibit Conserved Functionality in Nucleosome Remodeling and Histone Eviction in a Cytochrome c‐Dependent …
P Buzón, A Velázquez‐Cruz… - Advanced …, 2023 - Wiley Online Library
Chromatin homeostasis mediates essential processes in eukaryotes, where histone
chaperones have emerged as major regulatory factors during DNA replication, repair, and …
chaperones have emerged as major regulatory factors during DNA replication, repair, and …
PP2A complex disruptor SET prompts widespread hypertranscription of growth-essential genes in the pancreatic cancer cells
H Xu, D Wu, M Xiao, Y Lei, Y Lei, X Yu, S Shi - Science Advances, 2024 - science.org
Hyperactivation of the oncogenic transcription reflects the epigenetic plasticity of the cancer
cells. Su (var) 3-9, enhancer of zeste, Trithorax (SET) was described as a nuclear factor that …
cells. Su (var) 3-9, enhancer of zeste, Trithorax (SET) was described as a nuclear factor that …
Prothymosin-α plays a defensive role in retinal ischemia through necrosis and apoptosis inhibition
R Fujita, M Ueda, K Fujiwara, H Ueda - Cell Death & Differentiation, 2009 - nature.com
Prothymosin-α (ProTα) causes a switch in cell death mode from necrosis to neurotrophin-
reversible apoptosis in primary cultured cortical neurons. In the present study, post-ischemic …
reversible apoptosis in primary cultured cortical neurons. In the present study, post-ischemic …
Identification of prothymosin alpha (PTMA) as a biomarker for esophageal squamous cell carcinoma (ESCC) by label-free quantitative proteomics and Quantitative Dot …
Y Zhu, X Qi, C Yu, S Yu, C Zhang, Y Zhang, X Liu… - Clinical Proteomics, 2019 - Springer
Background Esophageal cancer (EC) is one of the malignant tumors with a poor prognosis.
The early stage of EC is asymptomatic, so identification of cancer biomarkers is important for …
The early stage of EC is asymptomatic, so identification of cancer biomarkers is important for …
Occurrence of incomplete paternal-chromosome retention in GH-transgenic coho salmon being assessed for reproductive containment by pressure-shock-induced …
RH Devlin, D Sakhrani, CA Biagi, KW Eom - Aquaculture, 2010 - Elsevier
The present study has assessed the efficacy of spontaneous and pressure-shock-induced
triploidy among 60,366 transgenic coho salmon progeny derived from crosses between …
triploidy among 60,366 transgenic coho salmon progeny derived from crosses between …
Tongue sole (Cynoglossus semilaevis) prothymosin alpha: Cytokine-like activities associated with the intact protein and the C-terminal region that lead to antiviral …
B Zhang, L Sun - Developmental & Comparative Immunology, 2015 - Elsevier
Prothymosin alpha (ProTα) is a small protein that in mammals is known to participate in
diverse biological processes including immunomodulation. In teleost, the immunological …
diverse biological processes including immunomodulation. In teleost, the immunological …