Integration site selection by retroviruses and transposable elements in eukaryotes
Transposable elements and retroviruses are found in most genomes, can be pathogenic
and are widely used as gene-delivery and functional genomics tools. Exploring whether …
and are widely used as gene-delivery and functional genomics tools. Exploring whether …
Accelerating Diverse Cell-Based Therapies Through Scalable Design
EL Peterman, D Ploessl… - Annual Review of …, 2024 - annualreviews.org
Augmenting cells with novel, genetically encoded functions will support therapies that
expand beyond natural capacity for immune surveillance and tissue regeneration. However …
expand beyond natural capacity for immune surveillance and tissue regeneration. However …
Transmicron: accurate prediction of insertion probabilities improves detection of cancer driver genes from transposon mutagenesis screens
Transposon screens are powerful in vivo assays used to identify loci driving carcinogenesis.
These loci are identified as Common Insertion Sites (CISs), ie regions with more transposon …
These loci are identified as Common Insertion Sites (CISs), ie regions with more transposon …
Prolonged activity of the transposase helper may raise safety concerns during DNA transposon-based gene therapy
DNA transposon-based gene delivery vectors represent a promising new branch of
randomly integrating vector development for gene therapy. For the side-by-side evaluation …
randomly integrating vector development for gene therapy. For the side-by-side evaluation …
[HTML][HTML] Роль транспозонов в структурной эволюции геномов эукариот
РН Мустафин - Гены и клетки, 2021 - cyberleninka.ru
В обзорной статье приведены работы, доказывающие происхождение центромерных
повторов от транспозонов у растений и животных. Мобильные элементы сохраняются …
повторов от транспозонов у растений и животных. Мобильные элементы сохраняются …
The role of transposons in the structural evolution of eukaryotic genomes
RN Mustafin - Genes & Cells, 2021 - genescells.ru
We presented evidence of the role of transposons in the occurrence of centromeric repeats
in plants and animals. During evolution, transposable elements are retained as part of …
in plants and animals. During evolution, transposable elements are retained as part of …
[HTML][HTML] TRIP through the chromatin: a high throughput exploration of enhancer regulatory landscapes
AV Pindyurin, J de Jong, W Akhtar - Genomics, 2015 - Elsevier
Enhancers are regulatory elements that promote gene expression in a spatio-temporal way
and are involved in a wide range of developmental and disease processes. Both the …
and are involved in a wide range of developmental and disease processes. Both the …