[HTML][HTML] Targeted and whole-genome sequencing reveal a north-south divide in P. falciparum drug resistance markers and genetic structure in Mozambique
C da Silva, S Boene, D Datta… - Communications …, 2023 - nature.com
Mozambique is one of the four African countries which account for over half of all malaria
deaths worldwide, yet little is known about the parasite genetic structure in that country. We …
deaths worldwide, yet little is known about the parasite genetic structure in that country. We …
[HTML][HTML] Arsinothricin Inhibits Plasmodium falciparum Proliferation in Blood and Blocks Parasite Transmission to Mosquitoes
Malaria, caused by Plasmodium protozoal parasites, remains a leading cause of morbidity
and mortality. The Plasmodium parasite has a complex life cycle, with asexual and sexual …
and mortality. The Plasmodium parasite has a complex life cycle, with asexual and sexual …
Prospective surveillance study to detect antimalarial drug resistance, gene deletions of diagnostic relevance and genetic diversity of Plasmodium falciparum in …
A Mayor, C da Silva, E Rovira-Vallbona… - BMJ open, 2022 - bmjopen.bmj.com
Introduction Genomic data constitute a valuable adjunct to routine surveillance that can
guide programmatic decisions to reduce the burden of infectious diseases. However …
guide programmatic decisions to reduce the burden of infectious diseases. However …
[HTML][HTML] High prevalence of Pfcrt 76T and Pfmdr1 N86 genotypes in malaria infected patients attending health facilities in East Shewa zone, Oromia Regional State …
Background Plasmodium falciparum resistance to series of anti-malarial drugs is a major
challenge in efforts to control and/or eliminate malaria globally. In 1998, following the …
challenge in efforts to control and/or eliminate malaria globally. In 1998, following the …
Whole-genome surveillance identifies markers of Plasmodium falciparum drug resistance and novel genomic regions under selection in Mozambique
E Coonahan, H Gage, D Chen, EV Noormahomed… - Mbio, 2023 - Am Soc Microbiol
The emergence of Plasmodium falciparum drug resistance threatens the efficacy of
antimalarial therapies globally. Population genomic studies have been instrumental in …
antimalarial therapies globally. Population genomic studies have been instrumental in …
[HTML][HTML] Anti-malarial resistance in Mozambique: Absence of Plasmodium falciparum Kelch 13 (K13) propeller domain polymorphisms associated with resistance to …
C da Silva, D Matias, B Dias, B Cancio, M Silva… - Malaria Journal, 2023 - Springer
Background Malaria remains one of the most serious public health problems in sub-Saharan
Africa and Mozambique is the world's fourth largest contributor, with 4.7% of disease cases …
Africa and Mozambique is the world's fourth largest contributor, with 4.7% of disease cases …
[HTML][HTML] Protocol: Prospective surveillance study to detect antimalarial drug resistance, gene deletions of diagnostic relevance and genetic diversity of Plasmodium …
A Mayor, C da Silva, E Rovira-Vallbona… - BMJ Open, 2022 - ncbi.nlm.nih.gov
Introduction Genomic data constitute a valuable adjunct to routine surveillance that can
guide programmatic decisions to reduce the burden of infectious diseases. However …
guide programmatic decisions to reduce the burden of infectious diseases. However …