PTEN in autism and neurodevelopmental disorders
S Rademacher, BJ Eickholt - Cold Spring …, 2019 - perspectivesinmedicine.cshlp.org
Phosphatase and tensin homolog (PTEN) is a classical tumor suppressor that antagonizes
phosphatidylinositol 3-phosphate kinase (PI3K)/AKT signaling. Although there is a strong …
phosphatidylinositol 3-phosphate kinase (PI3K)/AKT signaling. Although there is a strong …
Criss‐crossing autism spectrum disorder and adult neurogenesis
F Bicker, L Nardi, J Maier, V Vasic… - Journal of …, 2021 - Wiley Online Library
Autism spectrum disorder (ASD) comprises a group of multifactorial neurodevelopmental
disorders primarily characterized by deficits in social interaction and repetitive behavior …
disorders primarily characterized by deficits in social interaction and repetitive behavior …
[HTML][HTML] Pten is necessary for the quiescence and maintenance of adult muscle stem cells
Satellite cells (SCs) are myogenic stem cells required for regeneration of adult skeletal
muscles. A proper balance among quiescence, activation and differentiation is essential for …
muscles. A proper balance among quiescence, activation and differentiation is essential for …
Modeling Glaucoma: Retinal Ganglion Cells Generated from Induced Pluripotent Stem Cells of Patients with SIX6 Risk Allele Show Developmental Abnormalities
P Teotia, MJ Van Hook, CS Wichman… - Stem Cells, 2017 - academic.oup.com
Glaucoma represents a group of multifactorial diseases with a unifying pathology of
progressive retinal ganglion cell (RGC) degeneration, causing irreversible vision loss. To …
progressive retinal ganglion cell (RGC) degeneration, causing irreversible vision loss. To …
[HTML][HTML] Therapeutic role of PTEN in tissue regeneration for management of neurological disorders: stem cell behaviors to an in-depth review
Y Li, R Ma, X Hao - Cell Death & Disease, 2024 - nature.com
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) represents the initial
tumor suppressor gene identified to possess phosphatase activity, governing various …
tumor suppressor gene identified to possess phosphatase activity, governing various …
[HTML][HTML] PTEN expression is a prognostic marker for patients with non-small cell lung cancer: a systematic review and meta-analysis of the literature
J Xiao, CP Hu, BX He, X Chen, XX Lu, MX Xie, W Li… - Oncotarget, 2016 - ncbi.nlm.nih.gov
Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a known tumor
suppressor in non-small cell lung cancer (NSCLC). By performing a systematic review and …
suppressor in non-small cell lung cancer (NSCLC). By performing a systematic review and …
[HTML][HTML] A long journey before cycling: regulation of quiescence exit in adult muscle satellite cells
S Zhou, L Han, Z Wu - International Journal of Molecular Sciences, 2022 - mdpi.com
Skeletal muscle harbors a pool of stem cells called muscle satellite cells (MuSCs) that are
mainly responsible for its robust regenerative capacities. Adult satellite cells are mitotically …
mainly responsible for its robust regenerative capacities. Adult satellite cells are mitotically …
Pten associates with important gene regulatory network to fine‐tune Müller glia‐mediated zebrafish retina regeneration
Unlike mammals, zebrafish possess a remarkable ability to regenerate damaged retina after
an acute injury. Retina regeneration in zebrafish involves the induction of Müller glia …
an acute injury. Retina regeneration in zebrafish involves the induction of Müller glia …
[HTML][HTML] A WWP2–PTEN–KLF5 signaling axis regulates odontoblast differentiation and dentinogenesis in mice
J Fu, X Zhang, H Zheng, G Yang, Z Chen… - Journal of Biological …, 2022 - ASBMB
WW domain–containing E3 Ubiquitin-protein ligase 2 (WWP2) has been found to positively
regulate odontoblastic differentiation by monoubiquitinating the transcription factor Kruppel …
regulate odontoblastic differentiation by monoubiquitinating the transcription factor Kruppel …
[HTML][HTML] mTORC1 accelerates retinal development via the immunoproteasome
JH Choi, HS Jo, S Lim, HT Kim, KW Lee… - Nature …, 2018 - nature.com
The numbers and types of cells constituting vertebrate neural tissues are determined by
cellular mechanisms that couple neurogenesis to the proliferation of neural progenitor cells …
cellular mechanisms that couple neurogenesis to the proliferation of neural progenitor cells …