Phosphatase and tensin homolog (PTEN) is a classical tumor suppressor that antagonizes
phosphatidylinositol 3-phosphate kinase (PI3K)/AKT signaling. Although there is a strong …

Autism spectrum disorder (ASD) comprises a group of multifactorial neurodevelopmental
disorders primarily characterized by deficits in social interaction and repetitive behavior …

Satellite cells (SCs) are myogenic stem cells required for regeneration of adult skeletal
muscles. A proper balance among quiescence, activation and differentiation is essential for …

Glaucoma represents a group of multifactorial diseases with a unifying pathology of
progressive retinal ganglion cell (RGC) degeneration, causing irreversible vision loss. To …

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) represents the initial
tumor suppressor gene identified to possess phosphatase activity, governing various …

Phosphatase and tensin homolog deleted on chromosome 10 (PTEN) is a known tumor
suppressor in non-small cell lung cancer (NSCLC). By performing a systematic review and …

Skeletal muscle harbors a pool of stem cells called muscle satellite cells (MuSCs) that are
mainly responsible for its robust regenerative capacities. Adult satellite cells are mitotically …

Unlike mammals, zebrafish possess a remarkable ability to regenerate damaged retina after
an acute injury. Retina regeneration in zebrafish involves the induction of Müller glia …

WW domain–containing E3 Ubiquitin-protein ligase 2 (WWP2) has been found to positively
regulate odontoblastic differentiation by monoubiquitinating the transcription factor Kruppel …

The numbers and types of cells constituting vertebrate neural tissues are determined by
cellular mechanisms that couple neurogenesis to the proliferation of neural progenitor cells …