Cannabidiol for pain treatment: focus on pharmacology and mechanism of action
J Mlost, M Bryk, K Starowicz - International journal of molecular sciences, 2020 - mdpi.com
Cannabis has a long history of medical use. Although there are many cannabinoids present
in cannabis, Δ9tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are the two …
in cannabis, Δ9tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are the two …
[HTML][HTML] Molecular targets of cannabidiol in neurological disorders
Cannabis has a long history of anecdotal medicinal use and limited licensed medicinal use.
Until recently, alleged clinical effects from anecdotal reports and the use of licensed …
Until recently, alleged clinical effects from anecdotal reports and the use of licensed …
The polypharmacological effects of cannabidiol
J Castillo-Arellano, A Canseco-Alba, SJ Cutler, F León - Molecules, 2023 - mdpi.com
Cannabidiol (CBD) is a major phytocannabinoid present in Cannabis sativa (Linneo, 1753).
This naturally occurring secondary metabolite does not induce intoxication or exhibit the …
This naturally occurring secondary metabolite does not induce intoxication or exhibit the …
The direct actions of cannabidiol and 2-arachidonoyl glycerol at GABAA receptors
T Bakas, PS Van Nieuwenhuijzen, SO Devenish… - Pharmacological …, 2017 - Elsevier
Cannabidiol (CBD) is a major non-intoxicating component of cannabis and possesses anti-
epileptic, anxiolytic and anti-hyperalgesic properties. The mechanism of action of CBD in …
epileptic, anxiolytic and anti-hyperalgesic properties. The mechanism of action of CBD in …
Effects of cannabidiol (CBD) in neuropsychiatric disorders: A review of pre-clinical and clinical findings
Cannabis sativa (cannabis) is one of the oldest plants cultivated by men. Cannabidiol (CBD)
is the major non-psychomimetic compound derived from cannabis. It has been proposed to …
is the major non-psychomimetic compound derived from cannabis. It has been proposed to …
[HTML][HTML] Genome-wide association study implicates CHRNA2 in cannabis use disorder
Cannabis is the most frequently used illicit psychoactive substance worldwide; around one
in ten users become dependent. The risk for cannabis use disorder (CUD) has a strong …
in ten users become dependent. The risk for cannabis use disorder (CUD) has a strong …
[HTML][HTML] Cannabimimetic plants: are they new cannabinoidergic modulators?
Abstract Main Conclusion Phytochemicals and secondary metabolites able to interact with
the endocannabinoid system (Cannabimimetics) have been recently described in a broad …
the endocannabinoid system (Cannabimimetics) have been recently described in a broad …
Emerging evidence for the antidepressant effect of cannabidiol and the underlying molecular mechanisms
GP Silote, A Sartim, A Sales, A Eskelund… - Journal of chemical …, 2019 - Elsevier
Significant limitations with the currently available antidepressant treatment strategies have
inspired research on finding new and more efficient drugs to treat depression. Cannabidiol …
inspired research on finding new and more efficient drugs to treat depression. Cannabidiol …
Cannabidiol and substance use disorder: Dream or reality
S Karimi-Haghighi, Y Razavi, D Iezzi, AF Scheyer… - …, 2022 - Elsevier
Background Cannabidiol (CBD) is one of the major constituents of Cannabis sativa L. that
lacks psychotomimetic and rewarding properties and inhibits the rewarding and reinforcing …
lacks psychotomimetic and rewarding properties and inhibits the rewarding and reinforcing …
Global alignment and assessment of TRP channel transmembrane domain structures to explore functional mechanisms
KE Huffer, AA Aleksandrova, A Jara-Oseguera… - Elife, 2020 - elifesciences.org
The recent proliferation of published TRP channel structures provides a foundation for
understanding the diverse functional properties of this important family of ion channel …
understanding the diverse functional properties of this important family of ion channel …