[HTML][HTML] Advances in MALDI mass spectrometry imaging single cell and tissues
X Zhu, T Xu, C Peng, S Wu - Frontiers in Chemistry, 2022 - frontiersin.org
Compared to conventional optical microscopy techniques, mass spectrometry imaging (MSI)
or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique which can …
or imaging mass spectrometry (IMS) is a powerful, label-free analytical technique which can …
Recent developments of novel matrices and on-tissue chemical derivatization reagents for MALDI-MSI
Matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI-MSI) is a fast-
growing technique for visualization of the spatial distribution of the small molecular and …
growing technique for visualization of the spatial distribution of the small molecular and …
Sample preparation for mass spectrometry imaging: small mistakes can lead to big consequences
RJA Goodwin - Journal of proteomics, 2012 - Elsevier
Mass spectrometry imaging (MSI) enables the direct analysis of molecules from the surface
of a wide variety of samples, allowing the multiplex measurement of both abundance and …
of a wide variety of samples, allowing the multiplex measurement of both abundance and …
Mass spectrometry imaging for drug distribution studies
B Prideaux, M Stoeckli - Journal of proteomics, 2012 - Elsevier
Since its introduction mass spectrometry imaging (MSI) has proven to be a powerful tool for
the localization of molecules in biological tissues. In drug discovery and development …
the localization of molecules in biological tissues. In drug discovery and development …
Imaging mass spectrometry: instrumentation, applications, and combination with other visualization techniques
A Bodzon‐Kulakowska, P Suder - Mass spectrometry reviews, 2016 - Wiley Online Library
Imaging Mass Spectrometry (IMS) is strengthening its position as a valuable analytical tool. It
has unique ability to identify structures and to unravel molecular changes that occur in the …
has unique ability to identify structures and to unravel molecular changes that occur in the …
On‐tissue chemical derivatization in mass spectrometry imaging
C Harkin, KW Smith, FL Cruickshank… - Mass spectrometry …, 2022 - Wiley Online Library
Mass spectrometry imaging (MSI) combines molecular and spatial information in a valuable
tool for a wide range of applications. Matrix‐assisted laser desorption/ionization (MALDI) is …
tool for a wide range of applications. Matrix‐assisted laser desorption/ionization (MALDI) is …
Mass spectrometry imaging and its application in pharmaceutical research and development: A concise review
JG Swales, G Hamm, MR Clench… - International Journal of …, 2019 - Elsevier
Understanding the biodistribution, metabolism and accumulation of drugs in the body is a
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …
fundamental of pharmaceutical research and development. Mass Spectrometry imaging …
Mass spectrometry imaging in drug development
Drug discovery and development is a high-risk, expensive endeavor and it commonly takes
about 10− 15 years to obtain marketing approval from project inception. 1 Research efforts …
about 10− 15 years to obtain marketing approval from project inception. 1 Research efforts …
A critical and concise review of mass spectrometry applied to imaging in drug discovery
RJA Goodwin, Z Takats… - … : Advancing the Science of …, 2020 - journals.sagepub.com
During the past decade, mass spectrometry imaging (MSI) has become a robust and
versatile methodology to support modern pharmaceutical research and development. The …
versatile methodology to support modern pharmaceutical research and development. The …
Imaging mass spectrometry in drug development and toxicology
O Karlsson, J Hanrieder - Archives of toxicology, 2017 - Springer
During the last decades, imaging mass spectrometry has gained significant relevance in
biomedical research. Recent advances in imaging mass spectrometry have paved the way …
biomedical research. Recent advances in imaging mass spectrometry have paved the way …