Young-onset type 2 diabetes mellitus—Implications for morbidity and mortality

DJ Magliano, JW Sacre, JL Harding… - Nature Reviews …, 2020 - nature.com
Accumulating data suggest that type 2 diabetes mellitus (T2DM) in younger people (aged<
40 years), referred to as young-onset T2DM, has a more rapid deterioration of β-cell function …

ISPAD Clinical Practice Consensus Guidelines 2022: Type 2 diabetes in children and adolescents

AS Shah, PS Zeitler, J Wong, AS Pena… - Pediatric …, 2022 - Wiley Online Library
Since the 2018 ISPAD guidelines on this topic, follow‐up of large cohorts from around the
globe have continued informing the current incidence and prevalence of co‐morbidities and …

[HTML][HTML] Long-term complications in youth-onset type 2 diabetes

TODAY Study Group - New England Journal of Medicine, 2021 - Mass Medical Soc
Background The prevalence of type 2 diabetes in youth is increasing, but little is known
regarding the occurrence of related complications as these youths transition to adulthood …

Cardiovascular morbidity, diabetes and cancer risk among children and adolescents with severe obesity

CD Bendor, A Bardugo, O Pinhas-Hamiel… - Cardiovascular …, 2020 - Springer
Severe obesity among children and adolescents is a significant global public health
concern. The prevalence has markedly increased over the last decades, becoming common …

Association of type 1 diabetes vs type 2 diabetes diagnosed during childhood and adolescence with complications during teenage years and young adulthood

D Dabelea, JM Stafford, EJ Mayer-Davis, R D'Agostino… - Jama, 2017 - jamanetwork.com
Importance The burden and determinants of complications and comorbidities in
contemporary youth-onset diabetes are unknown. Objective To determine the prevalence of …

The changing face of diabetes complications

EW Gregg, N Sattar, MK Ali - The lancet Diabetes & endocrinology, 2016 - thelancet.com
The global increase in type 2 diabetes prevalence is well documented, but international
trends in complications of type 2 diabetes are less clear. The available data suggest large …

[HTML][HTML] Evaluation and management of youth-onset type 2 diabetes: a position statement by the American Diabetes Association

S Arslanian, F Bacha, M Grey, MD Marcus… - Diabetes …, 2018 - ncbi.nlm.nih.gov
Although all types of diabetes result in hyperglycemia, the pathophysiology of each type of
diabetes is different. These guidelines summarize available data specific to the …

[PDF][PDF] ISPAD clinical practice consensus guidelines 2018: type 2 diabetes mellitus in youth.

P Zeitler, S Arslanian, J Fu, O Pinhas‐Hamiel… - Pediatric diabetes, 2018 - bnsde.org
1. Undiagnosed type 2 diabetes mellitus (T2DM) is rare in the adolescent population, even
among high-risk individuals (A) 2. Generalized population screening of obese youth is …

Youth-onset type 2 diabetes consensus report: current status, challenges, and priorities

KJ Nadeau, BJ Anderson, EG Berg, JL Chiang… - Diabetes …, 2016 - Am Diabetes Assoc
Type 2 diabetes is a significant and increasing burden in adolescents and young adults.
Clear strategies for research, prevention, and treatment of the disease in these vulnerable …

Maternal obesity, diabetes during pregnancy and epigenetic mechanisms that influence the developmental origins of cardiometabolic disease in the offspring

P Agarwal, TS Morriseau, SM Kereliuk… - Critical reviews in …, 2018 - Taylor & Francis
Since 1980, global obesity has doubled, and the incidence of cardiometabolic diseases
such as type 2 diabetes and heart disease is also increasing. While genetic susceptibility …