Regulatory activities of transposable elements: from conflicts to benefits

EB Chuong, NC Elde, C Feschotte - Nature Reviews Genetics, 2017 - nature.com
Transposable elements (TEs) are a prolific source of tightly regulated, biochemically active
non-coding elements, such as transcription factor-binding sites and non-coding RNAs. Many …

[HTML][HTML] Genome-wide analysis of human long noncoding RNAs: a provocative review

CP Ponting, W Haerty - Annual review of genomics and human …, 2022 - annualreviews.org
Do long noncoding RNAs (lncRNAs) contribute little or substantively to human biology? To
address how lncRNA loci and their transcripts, structures, interactions, and functions …

Origins and evolutionary consequences of ancient endogenous retroviruses

WE Johnson - Nature Reviews Microbiology, 2019 - nature.com
Retroviruses infect a broad range of vertebrate hosts that includes amphibians, reptiles, fish,
birds and mammals. In addition, a typical vertebrate genome contains thousands of loci …

Defining functional DNA elements in the human genome

M Kellis, B Wold, MP Snyder… - Proceedings of the …, 2014 - National Acad Sciences
With the completion of the human genome sequence, attention turned to identifying and
annotating its functional DNA elements. As a complement to genetic and comparative …

[HTML][HTML] Transposable elements as essential elements in the control of gene expression

A Gebrie - Mobile DNA, 2023 - Springer
Interspersed repetitions called transposable elements (TEs), commonly referred to as mobile
elements, make up a significant portion of the genomes of higher animals. TEs contribute in …

[HTML][HTML] Non-coding RNA: what is functional and what is junk?

AF Palazzo, ES Lee - Frontiers in genetics, 2015 - frontiersin.org
The genomes of large multicellular eukaryotes are mostly comprised of non-protein coding
DNA. Although there has been much agreement that a small fraction of these genomes has …

[HTML][HTML] Transposable elements contribute to activation of maize genes in response to abiotic stress

I Makarevitch, AJ Waters, PT West, M Stitzer… - PLoS …, 2015 - journals.plos.org
Transposable elements (TEs) account for a large portion of the genome in many eukaryotic
species. Despite their reputation as “junk” DNA or genomic parasites deleterious for the …

The contributions of transposable elements to the structure, function, and evolution of plant genomes

JL Bennetzen, H Wang - Annual review of plant biology, 2014 - annualreviews.org
Transposable elements (TEs) are the key players in generating genomic novelty by a
combination of the chromosome rearrangements they cause and the genes that come under …

[HTML][HTML] Long terminal repeats: from parasitic elements to building blocks of the transcriptional regulatory repertoire

PJ Thompson, TS Macfarlan, MC Lorincz - Molecular cell, 2016 - cell.com
The life cycle of endogenous retroviruses (ERVs), also called long terminal repeat (LTR)
retrotransposons, begins with transcription by RNA polymerase II followed by reverse …

DNA methylation enables transposable element-driven genome expansion

W Zhou, G Liang, PL Molloy… - Proceedings of the …, 2020 - National Acad Sciences
Multicellular eukaryotic genomes show enormous differences in size. A substantial part of
this variation is due to the presence of transposable elements (TEs). They contribute …