Diet, microbiota and gut-lung connection

S Anand, SS Mande - Frontiers in microbiology, 2018 - frontiersin.org
The gut microbial community (Gut microbiota) is known to impact metabolic functions as well
as immune responses in our body. Diet plays an important role in determining the …

The multifaceted roles of breast milk antibodies

C Atyeo, G Alter - Cell, 2021 - cell.com
Neonates are born with an immature immune system and rely on the transfer of immunity
from their mothers. Maternal antibodies are transferred via the placenta and breast milk …

The maternal microbiota drives early postnatal innate immune development

M Gomez de Agüero, SC Ganal-Vonarburg, T Fuhrer… - Science, 2016 - science.org
Postnatal colonization of the body with microbes is assumed to be the main stimulus to
postnatal immune development. By transiently colonizing pregnant female mice, we show …

Rethinking mucosal antibody responses: IgM, IgG and IgD join IgA

K Chen, G Magri, EK Grasset, A Cerutti - Nature Reviews Immunology, 2020 - nature.com
Humoral immune responses at mucosal surfaces have historically focused on IgA. Growing
evidence highlights the complexity of IgA-inducing pathways and the functional impact of IgA …

IgA responses to microbiota

JJ Bunker, A Bendelac - Immunity, 2018 - cell.com
Various immune mechanisms are deployed in the mucosa to confront the immense diversity
of resident bacteria. A substantial fraction of the commensal microbiota is coated with …

[HTML][HTML] Programmed and environmental determinants driving neonatal mucosal immune development

N Torow, TW Hand, MW Hornef - Immunity, 2023 - cell.com
The mucosal immune system of neonates goes through successive, non-redundant phases
that support the developmental needs of the infant and ultimately establish immune …

Maternal IgA protects against the development of necrotizing enterocolitis in preterm infants

KP Gopalakrishna, BR Macadangdang, MB Rogers… - Nature medicine, 2019 - nature.com
Neonates are protected from colonizing bacteria by antibodies secreted into maternal milk.
Necrotizing enterocolitis (NEC) is a disease of neonatal preterm infants with high morbidity …

How nutrition and the maternal microbiota shape the neonatal immune system

AJ Macpherson, MG De Agüero… - Nature Reviews …, 2017 - nature.com
The mucosal surfaces of mammals are densely colonized with microorganisms that are
commonly referred to as the commensal microbiota. It is believed that the fetus in utero is …

[HTML][HTML] Maternal gut bacteria drive intestinal inflammation in offspring with neurodevelopmental disorders by altering the chromatin landscape of CD4+ T cells

E Kim, D Paik, RN Ramirez, DG Biggs, Y Park… - Immunity, 2022 - cell.com
Children with autism spectrum disorders often display dysregulated immune responses and
related gastrointestinal symptoms. However, the underlying mechanisms leading to the …

The immature gut barrier and its importance in establishing immunity in newborn mammals

B Weström, E Arévalo Sureda, K Pierzynowska… - Frontiers in …, 2020 - frontiersin.org
The gut is an efficient barrier which protects against the passage of pathogenic
microorganisms and potential harmful macromolecules into the body, in addition to its …