Optogenetics combines genetics and biophotonics to enable noninvasive control of
biological processes with high spatiotemporal precision. When engineered into protein …

This review adds the bilin-binding phytochromes to the Chemical Reviews thematic issue
“Optogenetics and Photopharmacology”. The work is structured into two parts. We first …

Light perception is indispensable for plants to respond adequately to external cues and is
linked to proteolysis of key transcriptional regulators. To provide synthetic light control of …

We show that difficulties in regulating cellular behavior with synthetic biological circuits may
be circumvented using in silico feedback control. By tracking a circuit's output in …

Yeast is an ideal organism for the development and application of synthetic biology, yet
there remain relatively few well-characterised biological parts suitable for precise …

Optogenetics combines light and genetics to enable precise control of living cells, tissues,
and organisms with tailored functions. Optogenetics has the advantages of …

Phytochrome A (phyA) is the only photoreceptor in plants, initiating responses in far-red light
and, as such, essential for survival in canopy shade. Although the absorption and the ratio of …

Synthetic biologists construct biological components and systems to look into biological
phenomena and drive a myriad of practical applications that aim to tackle current global …

Metabolic engineering has enabled us to develop strains suitable for their use as microbial
factories of chemicals and materials from renewable sources. It has recently become more …

Chemical induction is one of the most common modalities used to manipulate gene
expression in living systems. However, chemical induction can be toxic or expensive that …