Four main histological subtypes of ovarian cancer exist: serous (the most frequent),
endometrioid, mucinous and clear cell; in each subtype, low and high grade. The large …

The aim of this study was to evaluate the distribution of inhibin/activin alpha, beta (A) and
beta (B) subunits and follistatin in immature oocytes and in matured oocytes before and after …

The cancer stem cell (CSC) model proposes that tumors have a hierarchical organization in
which only some cells indefinitely self-renew and thereby sustain tumor growth. In addition …

Aldehyde dehydrogenase 1 (ALDH1) activity has now been employed successfully as a
cancer stem cells (CSCs) marker in various tumors. We wanted to investigate whether …

An altered metabolism during ovarian cancer progression allows for increased
macromolecular synthesis and unrestrained growth. However, the metabolic phenotype of …

In 2013 there will be an estimated 22,240 new diagnoses and 14,030 deaths from ovarian
cancer in the United States. Despite the improved surgical approach and the novel active …

Recent data suggest that rare stem cell populations with the capacity to self renew and drive
tumor formation are a feature of solid tumors. Several investigators have identified putative …

Recruitment and localization of endothelial precursors within tumors is a potential area for
the development of therapeutics, because their functional contribution to tumor vasculature …

Increasing evidence suggests an association between cancer stem cells and the tumor
microenvironment. Ovarian cancer stem cell (OCSC) factors can influence the tumor …

Ovarian cancer is the most common type of gynecologic malignancy. Despite advances in
surgery and chemotherapy, the survival rate is still low since most ovarian cancers relapse …