Computational modelling of the lungs is an active field of study that integrates computational
advances with lung biophysics, biomechanics, physiology and medical imaging to promote …

Modelling the mechanical behaviour of biological tissues is of vital importance for clinical
applications. It is necessary for surgery simulation, tissue engineering, finite element …

We introduce a finite-element-model-updating-based open-source framework to identify
mechanical parameters of heterogeneous hyperelastic materials from in silico generated full …

Irreversible alveolar airspace enlargement is the main characteristic of pulmonary
emphysema, which has been extensively studied using animal models. While the alterations …

To unravel processes that lead to the growth of solid tumours, it is necessary to link
knowledge of cancer biology with the physical properties of the tumour and its interaction …

Mechanical ventilation has been a vital treatment for Covid-19 patients with respiratory
failure. Lungs assisted with mechanical ventilators present a wide variability in their …

Lung injuries are common among those who suffer an impact or trauma. The relative
severity of injuries up to physical tearing of tissue have been documented in clinical studies …

Characterizing material properties of lung parenchyma is essential in order to describe and
predict the mechanical behavior of the lung in health and disease. Hence, we aim to identify …

In the lungs, increased vascular permeability can lead to acute lung injury. Because
vascular permeability is regulated primarily by endothelial cells, many researchers have …

In this study, we present a method to experimentally quantify and numerically identify the
constituent-specific material behavior of soft biological tissues. This allows the clear …