Antimicrobial resistance: an antimicrobial/diagnostic stewardship and infection prevention approach

EJ Septimus - Medical Clinics, 2018 - medical.theclinics.com
Antimicrobial resistance (AR) is one of the most serious public health threats today, which
has been accelerated by the overuse and misuse of antimicrobials in humans and animals …

Maximising access to achieve appropriate human antimicrobial use in low-income and middle-income countries

M Mendelson, JA Røttingen, U Gopinathan, DH Hamer… - The Lancet, 2016 - thelancet.com
Access to quality-assured antimicrobials is regarded as part of the human right to health, yet
universal access is often undermined in low-income and middle-income countries. Lack of …

Sepsis-associated acute kidney injury in the intensive care unit: incidence, patient characteristics, timing, trajectory, treatment, and associated outcomes. A multicenter …

KC White, A Serpa-Neto, R Hurford, P Clement… - Intensive care …, 2023 - Springer
Abstract Purpose The Acute Disease Quality Initiative (ADQI) Workgroup recently released a
consensus definition of sepsis-associated acute kidney injury (SA-AKI), combining Sepsis-3 …

Antimicrobial stewardship across 47 South African hospitals: an implementation study

AJ Brink, AP Messina, C Feldman… - The Lancet Infectious …, 2016 - thelancet.com
Background The available data on antimicrobial stewardship programmes in Africa are
scarce. The aims of this study were to assess the implementation of an antimicrobial …

Incidence and outcomes of non–ventilator-associated hospital-acquired pneumonia in 284 US hospitals using electronic surveillance criteria

BE Jones, AL Sarvet, J Ying, R Jin… - JAMA Network …, 2023 - jamanetwork.com
Importance Non–ventilator-associated hospital-acquired pneumonia (NV-HAP) is a common
and deadly hospital-acquired infection. However, inconsistent surveillance methods and …

A molecular host response assay to discriminate between sepsis and infection-negative systemic inflammation in critically ill patients: discovery and validation in …

L McHugh, TA Seldon, RA Brandon, JT Kirk… - PLoS …, 2015 - journals.plos.org
Background Systemic inflammation is a whole body reaction having an infection-positive (ie,
sepsis) or infection-negative origin. It is important to distinguish between these two …

Evaluation of point-of-care multiplex polymerase chain reaction in guiding antibiotic treatment of patients acutely admitted with suspected community-acquired …

MB Cartuliares, FS Rosenvinge, CB Mogensen… - PLoS …, 2023 - journals.plos.org
Background Rapid and accurate detection of pathogens is needed in community-acquired
pneumonia (CAP) to enable appropriate antibiotics and to slow the development of antibiotic …

[PDF][PDF] A study of unnecessary use of antibiotics at a tertiary care hospital: Urgent need to implement antimicrobial stewardship programs

YB Bin, A Rozina, M Junaid, K Saima… - Journal of Young …, 2015 - jyoungpharm.org
Background: The resistant bacteria are on upward trend in the third world countries
especially in Pakistan. One of the reasons is injudicious prescription of antibiotics. The aim …

Advances in antibiotic therapy in the critically ill

JL Vincent, M Bassetti, B François, G Karam, J Chastre… - Critical Care, 2016 - Springer
Infections occur frequently in critically ill patients and their management can be challenging
for various reasons, including delayed diagnosis, difficulties identifying causative …

Antibiotic stewardship in the intensive care unit. An official American Thoracic Society workshop report in collaboration with the AACN, CHEST, CDC, and SCCM

RG Wunderink, A Srinivasan, PS Barie… - Annals of the …, 2020 - atsjournals.org
Intensive care units (ICUs) are an appropriate focus of antibiotic stewardship program efforts
because a large proportion of any hospital's use of parenteral antibiotics, especially broad …