Accurate cell classification is the groundwork for downstream analysis of single-cell
sequencing data, yet how to identify true marker genes for different cell types still remains a …

Culturing skin cells outside of the body has been a cornerstone of dermatological
investigation for many years; however, human skin equivalent systems typically lack the full …

We have examined the developmental origins of Ng2+ perivascular cell populations that
adhere to the basement membrane of blood vessels, and their contribution to wound …

The human mononuclear phagocyte (MP) system, which includes dendritic cells, monocytes,
and macrophages, is a critical regulator of innate and adaptive immune responses. During …

Chronic pain and its underlying biological mechanisms have been studied for many
decades, with a myriad of molecules, receptors and cell types known to contribute to …

Background MicroRNAs are small regulatory molecules that are dysregulated in psoriasis.
Despite previous efforts, much is unknown about the regulatory mechanisms of psoriasis …

Chronic pain and its underlying biological mechanisms have been studied for many
decades, with a myriad of molecules, receptors and cell types known to contribute to …

Mammalian skin is composed of two layers, the epidermis, and the underlying dermis. The
main cell type within the dermis are fibroblasts which have distinct functions during skin …