2019 ESC Guidelines for the diagnosis and management of acute pulmonary embolism developed in collaboration with the European Respiratory Society (ERS) The …

SV Konstantinides, G Meyer, C Becattini… - European heart …, 2020 - academic.oup.com
determination and the implementation of preventive, diagnostic or therapeutic medical
strategies. However, the ESC Guidelines do not override in any way whatsoever the …

A test in context: D-dimer

JI Weitz, JC Fredenburgh, JW Eikelboom - Journal of the American College …, 2017 - jacc.org
D-dimer is a soluble fibrin degradation product that results from ordered breakdown of
thrombi by the fibrinolytic system. Numerous studies have shown that D-dimer serves as a …

Deep vein thrombosis and pulmonary embolism

M Di Nisio, N van Es, HR Büller - The Lancet, 2016 - thelancet.com
Deep vein thrombosis and pulmonary embolism, collectively referred to as venous
thromboembolism, constitute a major global burden of disease. The diagnostic work-up of …

Age-adjusted D-dimer cutoff levels to rule out pulmonary embolism: the ADJUST-PE study

M Righini, J Van Es, PL Den Exter, PM Roy… - Jama, 2014 - jamanetwork.com
Importance D-dimer measurement is an important step in the diagnostic strategy of clinically
suspected acute pulmonary embolism (PE), but its clinical usefulness is limited in elderly …

The D‐dimer assay

ED Johnson, JC Schell… - American journal of …, 2019 - Wiley Online Library
D‐dimer is an indirect marker of fibrinolysis and fibrin turnover; this molecule exhibits unique
properties as a biological marker of hemostatic abnormalities as well as an indicator of …

2014 ESC Guidelines on the diagnosis and management of acute pulmonary embolism: The Task Force for the Diagnosis and Management of Acute Pulmonary …

Authors/Task Force Members… - European heart …, 2014 - academic.oup.com
The task of developing ESC Guidelines covers not only the integration of the most recent
research, but also the creation of educational tools and implementation programmes for the …

Review of D‐dimer testing: Good, Bad, and Ugly

LA Linkins, S Takach Lapner - International Journal of …, 2017 - Wiley Online Library
D‐dimer assays are commonly used in clinical practice to exclude a diagnosis of deep vein
thrombosis or pulmonary embolism. More recently, they have been also been used to guide …

Diagnosis of DVT: antithrombotic therapy and prevention of thrombosis: American College of Chest Physicians evidence-based clinical practice guidelines

SM Bates, R Jaeschke, SM Stevens, S Goodacre… - Chest, 2012 - Elsevier
Background Objective testing for DVT is crucial because clinical assessment alone is
unreliable and the consequences of misdiagnosis are serious. This guideline focuses on the …

Prediction of venous thromboembolism in cancer patients

C Ay, D Dunkler, C Marosi, AL Chiriac… - Blood, The Journal …, 2010 - ashpublications.org
The risk of venous thromboembolism (VTE) is increased in cancer patients. To improve
prediction of VTE in cancer patients, we performed a prospective and observational cohort …

D-dimer: Preanalytical, analytical, postanalytical variables, and clinical applications

J Favresse, G Lippi, PM Roy, B Chatelain… - Critical reviews in …, 2018 - Taylor & Francis
D-dimer is a soluble fibrin degradation product deriving from the plasmin-mediated
degradation of cross-linked fibrin. D-dimer can hence be considered a biomarker of …