Alzheimer's disease (AD) is the most prevalent form of dementia. Despite decades of
research following several theoretical and clinical lines, all existing treatments for the …

The idea of reserve against brain damage stems from the repeated observation that there
does not appear to be a direct relationship between the degree of brain pathology or brain …

To improvethe diagnosticperformanceof PET as an aid in
evaluatingpatientssuspectedofhawig@ 4Jzhalmer'sdisease, we devalopeda …

Late-onset dementia is a major health concern in the ageing population. Alzheimer's
disease (AD) accounts for the largest proportion (65–70%) of dementia cases in the older …

The demographics of aging suggest a great need for the early diagnosis of dementia and
the development of preventive strategies. Neuropathology and structural MRI studies have …

One of the main features of Alzheimer's disease (AD) is the severe reduction of the cerebral
metabolic rate for glucose (CMRglc). In vivo imaging using positron emission tomography …

A higher prevalence of dementia in individuals with fewer years of education has suggested
that education may protect against Alzheimer's disease (AD). We tested whether individuals …

Serotonin (5-HT) neuron and neurotransmitter loss in normal aging and neuropsychiatric
diseases of late life may contribute to behavioral changes commonly observed in the elderly …

Nosologically, Alzheimer disease is not a single disorder in spite of a common clinical
phenotype. Etiologically, two different types or even more exist.(1) In a minority of about 5 …

We used MRI volume sampling with coregistered and atrophy corrected FDG-PET scans to
test three hypotheses: 1) hippocampal formation measures are superior to temporal …