The Ruminococci: key symbionts of the gut ecosystem
AJ La Reau, G Suen - Journal of microbiology, 2018 - Springer
Mammalian gut microbial communities form intricate mutualisms with their hosts, which have
profound implications on overall health. One group of important gut microbial mutualists are …
profound implications on overall health. One group of important gut microbial mutualists are …
Microbiome therapeutics—advances and challenges
The microbial community that lives on and in the human body exerts a major impact on
human health, from metabolism to immunity. In order to leverage the close associations …
human health, from metabolism to immunity. In order to leverage the close associations …
Novel bile acid biosynthetic pathways are enriched in the microbiome of centenarians
Y Sato, K Atarashi, DR Plichta, Y Arai, S Sasajima… - Nature, 2021 - nature.com
Centenarians have a decreased susceptibility to ageing-associated illnesses, chronic
inflammation and infectious diseases 1, 2, 3. Here we show that centenarians have a distinct …
inflammation and infectious diseases 1, 2, 3. Here we show that centenarians have a distinct …
Global chemical effects of the microbiome include new bile-acid conjugations
A mosaic of cross-phylum chemical interactions occurs between all metazoans and their
microbiomes. A number of molecular families that are known to be produced by the …
microbiomes. A number of molecular families that are known to be produced by the …
Reverse metabolomics for the discovery of chemical structures from humans
Determining the structure and phenotypic context of molecules detected in untargeted
metabolomics experiments remains challenging. Here we present reverse metabolomics as …
metabolomics experiments remains challenging. Here we present reverse metabolomics as …
Assessment of variation in microbial community amplicon sequencing by the Microbiome Quality Control (MBQC) project consortium
In order for human microbiome studies to translate into actionable outcomes for health, meta-
analysis of reproducible data from population-scale cohorts is needed. Achieving sufficient …
analysis of reproducible data from population-scale cohorts is needed. Achieving sufficient …
Stability and biological activity of wild blueberry (Vaccinium angustifolium) polyphenols during simulated in vitro gastrointestinal digestion
J Correa-Betanzo, E Allen-Vercoe, J McDonald… - Food chemistry, 2014 - Elsevier
Wild blueberries are rich in polyphenols and have several potential health benefits.
Understanding the factors that affect the bioaccessibility and bioavailability of polyphenols is …
Understanding the factors that affect the bioaccessibility and bioavailability of polyphenols is …
Experimental models to study intestinal microbes–mucus interactions in health and disease
L Etienne-Mesmin, B Chassaing… - FEMS microbiology …, 2019 - academic.oup.com
ABSTRACT A close symbiotic relationship exists between the intestinal microbiota and its
host. A critical component of gut homeostasis is the presence of a mucus layer covering the …
host. A critical component of gut homeostasis is the presence of a mucus layer covering the …
Capturing the diversity of the human gut microbiota through culture-enriched molecular profiling
JT Lau, FJ Whelan, I Herath, CH Lee, SM Collins… - Genome medicine, 2016 - Springer
Background The human gut microbiota has been implicated in most aspects of health and
disease; however, most of the bacteria in this community are considered unculturable, so …
disease; however, most of the bacteria in this community are considered unculturable, so …
Inhibiting growth of Clostridioides difficile by restoring valerate, produced by the intestinal microbiota
Background & Aims Fecal microbiota transplantation (FMT) is effective for treating recurrent
Clostridioides difficile infection (CDI), but there are concerns about its long-term safety …
Clostridioides difficile infection (CDI), but there are concerns about its long-term safety …