Bovine respiratory syncytial virus infection

JF Valarcher, G Taylor - Veterinary research, 2007 - hal.science
Bovine respiratory syncytial virus (BRSV) belongs to the pneumovirus genus within the
family Paramyxoviridae and is a major cause of respiratory disease in young calves. BRSV …

Alphavirus polymerase and RNA replication

MK Pietilä, K Hellström, T Ahola - Virus research, 2017 - Elsevier
Alphaviruses are typically arthropod-borne, and many are important pathogens such as
chikungunya virus. Alphaviruses encode four nonstructural proteins (nsP1–4), initially …

[HTML][HTML] A condensate-hardening drug blocks RSV replication in vivo

J Risso-Ballester, M Galloux, J Cao, R Le Goffic… - Nature, 2021 - nature.com
Biomolecular condensates have emerged as an important subcellular organizing principle.
Replication of many viruses, including human respiratory syncytial virus (RSV), occurs in …

Programmable inhibition and detection of RNA viruses using Cas13

CA Freije, C Myhrvold, CK Boehm, AE Lin, NL Welch… - Molecular cell, 2019 - cell.com
The CRISPR effector Cas13 could be an effective antiviral for single-stranded RNA (ssRNA)
viruses because it programmably cleaves RNAs complementary to its CRISPR RNA …

A single-dose live-attenuated YF17D-vectored SARS-CoV-2 vaccine candidate

L Sanchez-Felipe, T Vercruysse, S Sharma, J Ma… - Nature, 2021 - nature.com
The expanding pandemic of coronavirus disease 2019 (COVID-19) requires the
development of safe, efficacious and fast-acting vaccines. Several vaccine platforms are …

Neutralizing activity of Sputnik V vaccine sera against SARS-CoV-2 variants

S Ikegame, MNA Siddiquey, CT Hung, G Haas… - Nature …, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected at least 180
million people since its identification as the cause of the current COVID-19 pandemic. The …

[HTML][HTML] Replication-competent vesicular stomatitis virus vaccine vector protects against SARS-CoV-2-mediated pathogenesis in mice

JB Case, PW Rothlauf, RE Chen, NM Kafai, JM Fox… - Cell host & …, 2020 - cell.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused millions of
human infections, and an effective vaccine is critical to mitigate coronavirus-induced disease …

Negri bodies are viral factories with properties of liquid organelles

J Nikolic, R Le Bars, Z Lama, N Scrima… - Nature …, 2017 - nature.com
Replication of Mononegavirales occurs in viral factories which form inclusions in the host-
cell cytoplasm. For rabies virus, those inclusions are called Negri bodies (NBs). We report …

[HTML][HTML] Neutralizing antibody and soluble ACE2 inhibition of a replication-competent VSV-SARS-CoV-2 and a clinical isolate of SARS-CoV-2

JB Case, PW Rothlauf, RE Chen, Z Liu, H Zhao… - Cell host & …, 2020 - cell.com
Antibody-based interventions against SARS-CoV-2 could limit morbidity, mortality, and
possibly transmission. An anticipated correlate of such countermeasures is the level of …

The coronavirus spike protein is a class I virus fusion protein: structural and functional characterization of the fusion core complex

BJ Bosch, R Van der Zee, CAM De Haan… - Journal of …, 2003 - Am Soc Microbiol
Coronavirus entry is mediated by the viral spike (S) glycoprotein. The 180-kDa oligomeric S
protein of the murine coronavirus mouse hepatitis virus strain A59 is posttranslationally …