Information theory: new look at oncogenic signaling pathways
KA Zielińska, VL Katanaev - Trends in cell biology, 2019 - cell.com
Sustained pro-proliferative signaling is one of the hallmarks of cancer. Although it is
generally understood that the oncogenic signaling pathways are overactivated, or at least …
generally understood that the oncogenic signaling pathways are overactivated, or at least …
Navigating multi-scale cancer systems biology towards model-driven clinical oncology and its applications in personalized therapeutics
MN Gondal, SU Chaudhary - Frontiers in Oncology, 2021 - frontiersin.org
Rapid advancements in high-throughput omics technologies and experimental protocols
have led to the generation of vast amounts of scale-specific biomolecular data on cancer …
have led to the generation of vast amounts of scale-specific biomolecular data on cancer …
Counting processes with piecewise-deterministic Markov conditional intensity: Asymptotic analysis, implementation and information-theoretic use
M Sinzger-D'Angelo, H Koeppl - IEEE Transactions on …, 2023 - ieeexplore.ieee.org
Counting processes (CPs) are important mathematical models with a variety of applications
in signal processing, telecommunication, queuing, neuroscience, systems and synthetic …
in signal processing, telecommunication, queuing, neuroscience, systems and synthetic …
Potential therapeutic targets of gastric cancer explored under endogenous network modeling of clinical data
X Zhang, YC Chen, M Yao, R Xiong, B Liu, X Zhu… - Scientific Reports, 2024 - nature.com
Improvement in the survival rate of gastric cancer, a prevalent global malignancy and the
leading cause of cancer-related mortality calls for more avenues in molecular therapy. This …
leading cause of cancer-related mortality calls for more avenues in molecular therapy. This …
Decoding cellular communication: An information theoretic perspective on cytokine and endocrine signaling
F Schaper, T Jetka, A Dittrich - Current Opinion in Endocrine and Metabolic …, 2022 - Elsevier
Humoral communication is mediated by complex signaling pathways that are
heterogeneously activated in individual cells. According to Shannon's information theory …
heterogeneously activated in individual cells. According to Shannon's information theory …
Computation in bacterial communities
G Ostovar, KL Naughton, JQ Boedicker - Physical Biology, 2020 - iopscience.iop.org
Bacteria across many scales are involved in a dynamic process of information exchange to
coordinate activity and community structure within large and diverse populations. The …
coordinate activity and community structure within large and diverse populations. The …
Computation by natural systems
Computation is a useful concept far beyond the disciplinary boundaries of computer science.
Perhaps the most important class of natural computers can be found in biological systems …
Perhaps the most important class of natural computers can be found in biological systems …
ACID: A Low Dimensional Characterization of Markov-Modulated and Self-Exciting Counting Processes
M Sinzger-D'Angelo, H Koeppl - arXiv preprint arXiv:2205.07011, 2022 - arxiv.org
The conditional intensity (CI) of a counting process $ Y_t $ is based on the minimal
knowledge $\mathcal {F} _t^ Y $, ie, on the observation of $ Y_t $ alone. Prominently, the …
knowledge $\mathcal {F} _t^ Y $, ie, on the observation of $ Y_t $ alone. Prominently, the …
Therapeutic targets of gastric cancer explored under endogenous network modeling of clinical data
X Zhang, C Yong-Cong, M Yao, R Xiong, B Liu, X Zhu… - 2024 - researchsquare.com
Improvement in the survival rate of gastric cancer, a prevalent global malignancy and the
leading cause of cancer-related mortality calls for more avenues in molecular therapy. This …
leading cause of cancer-related mortality calls for more avenues in molecular therapy. This …
Navigating Multi-scale Cancer Systems Biology towards Model-driven Personalized Therapeutics
MN Gondal, SU Chaudhary - bioRxiv, 2021 - biorxiv.org
Rapid advancements in high-throughput omics technologies and experimental protocols
have led to the generation of vast amounts of biomolecular data on cancer that now …
have led to the generation of vast amounts of biomolecular data on cancer that now …