Unlike natural macromolecules (eg, nucleic acids and proteins) possessing precisely
defined molar mass, chain sequence, chirality, and topology, synthetic polymers are typically …

Natural macromolecules, such as proteins and nucleic acids, display various complex
functionalities in biological systems. These functionalities depend on the macromolecular …

Hydrophilic polymers are a major class of polymers in polymer science. They are found in
broad range of applications from superabsorbers to drug-delivery. In recent years, a plethora …

Conspectus The preparation of discrete and well-defined polymers is an emerging strategy
for emulating the remarkable precision achieved by macromolecular synthesis in nature …

Single-unit monomer insertion (SUMI) has become an important strategy for the synthesis of
sequence-controlled vinyl polymers due to its strong versatility and high efficiency. However …

Synthetic polymers have been extensively used in biomedical fields for imaging and
therapeutic purposes. These macromolecular nanomedicines have shown unique …

Block copolymers are widely used in many applications due to their spontaneous self-
assembly into a variety of nanoscale morphologies. However, a grand challenge in …

To emulate the ordered arrangement of monomer units found in natural macromolecules,
single-unit monomer insertion (SUMI) have emerged as a potent technique for synthesizing …

The development of synthetic oligomers as discrete single molecular entities with accurate
control over the number and nature of functional groups along the backbone has enabled a …

PEGylation, which covalently modifies small-molecule drugs, peptides and proteins with
polyethylene glycol (PEG) to improve their pharmacokinetics and efficacy, has become one …