A review of the biological role of miRNAs in prostate cancer suppression and progression

AS Doghish, A Ismail, HA El-Mahdy, MA Elkady… - International journal of …, 2022 - Elsevier
Prostate cancer (PC) is the third-leading cause of cancer-related deaths worldwide.
Although the current treatment strategies are progressing rapidly, PC is still representing a …

[HTML][HTML] The promising role of new molecular biomarkers in prostate cancer: From coding and non-coding genes to artificial intelligence approaches

AP Alarcón-Zendejas, A Scavuzzo… - Prostate cancer and …, 2022 - nature.com
Background Risk stratification or progression in prostate cancer is performed with the
support of clinical-pathological data such as the sum of the Gleason score and serum levels …

FTO-stabilized miR-139–5p targets ZNF217 to suppress prostate cancer cell malignancies by inactivating the PI3K/Akt/mTOR signal pathway

B Azhati, A Reheman, D Dilixiati, M Rexiati - Archives of Biochemistry and …, 2023 - Elsevier
As one of the most important demethylases for RNA N6-methyladenosine (m6A)
modifications, fat mass and obesity-associated protein (FTO) plays anti-cancer role during …

[HTML][HTML] The mechanistic roles of sirtuins in breast and prostate cancer

CI Onyiba, CJ Scarlett, J Weidenhofer - Cancers, 2022 - mdpi.com
Simple Summary There are diverse reports of the dual role of sirtuin genes and proteins in
breast and prostate cancers. This review discusses the current information on the tumor …

[HTML][HTML] Urinary microRNAs and their significance in prostate cancer diagnosis: a 5-year update

J Juracek, M Madrzyk, M Stanik, O Slaby - Cancers, 2022 - mdpi.com
Simple Summary Current diagnostics of prostate cancer often show unsatisfactory results,
leading to delayed detection or overtreatment. Urinary microRNAs are a class of promising …

[HTML][HTML] Lipid metabolism-related miRNAs with potential diagnostic roles in prostate cancer

T Zhai, M Dou, Y Ma, H Wang, F Liu, L Zhang… - Lipids in Health and …, 2023 - Springer
Abstract Background Prostate cancer (PCa), the second most prevalent solid tumor among
men worldwide, has caused greatly increasing mortality in PCa patients. The effects of lipid …

METTL3 promotes prostate cancer progression by regulating miR‐182 maturation in m6A‐dependent manner

D Wang, X Wang, B Huang, Y Zhao, W Tu, X Jin… - Andrologia, 2022 - Wiley Online Library
METTL3 was known to run through the whole cycle of RNA. It relied on m6A modification in
the mRNAs of cancer‐related genes to regulate tumour progression. The development of …

Suppressive function of bone marrow-derived mesenchymal stem cell-derived exosomal microRNA-187 in prostate cancer

C Li, Z Sun, Y Song, Y Zhang - Cancer Biology & Therapy, 2022 - Taylor & Francis
Application of bone marrow-derived mesenchymal stem cell-derived exosomes (BMSC-
exos) in cancer treatment has been widely studied. Here, we elaborated the function of …

MiR‐145‐5p Inhibits the Invasion of Prostate Cancer and Induces Apoptosis by Inhibiting WIP1

J Sun, L Deng, Y Gong - Journal of oncology, 2021 - Wiley Online Library
Prostate cancer (PCa) is a common malignant tumor of the male genitourinary system that
seriously affects the quality of life of patients. Studying the pathogenesis and therapeutic …

miRNAs and radiotherapy response in prostate cancer

MY Konoshenko, OE Bryzgunova, PP Laktionov - Andrology, 2021 - Wiley Online Library
Background Gaining insight into microRNAs (miRNAs) and genes that regulate the
therapeutic response of cancer diseases in general and prostate cancer (PCa) in particular …