[HTML][HTML] DNA vaccines against COVID-19: Perspectives and challenges
MM Silveira, GMSG Moreira, M Mendonça - Life sciences, 2021 - Elsevier
Abstract The coronavirus disease 2019 (COVID-19) is caused by a novel coronavirus known
as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is associated …
as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which is associated …
[HTML][HTML] Exploitation of glycosylation in enveloped virus pathobiology
Y Watanabe, TA Bowden, IA Wilson… - Biochimica et Biophysica …, 2019 - Elsevier
Glycosylation is a ubiquitous post-translational modification responsible for a multitude of
crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to …
crucial biological roles. As obligate parasites, viruses exploit host-cell machinery to …
Cross-neutralization of SARS-CoV-2 by a human monoclonal SARS-CoV antibody
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a newly emerged
coronavirus that is responsible for the current pandemic of coronavirus disease 2019 …
coronavirus that is responsible for the current pandemic of coronavirus disease 2019 …
[HTML][HTML] Structures of human antibodies bound to SARS-CoV-2 spike reveal common epitopes and recurrent features of antibodies
CO Barnes, AP West, KE Huey-Tubman… - Cell, 2020 - cell.com
Neutralizing antibody responses to coronaviruses mainly target the receptor-binding domain
(RBD) of the trimeric spike. Here, we characterized polyclonal immunoglobulin Gs (IgGs) …
(RBD) of the trimeric spike. Here, we characterized polyclonal immunoglobulin Gs (IgGs) …
Emerging COVID-19 coronavirus: glycan shield and structure prediction of spike glycoprotein and its interaction with human CD26
N Vankadari, JA Wilce - Emerging microbes & infections, 2020 - Taylor & Francis
The recent outbreak of pneumonia-causing COVID-19 in China is an urgent global public
health issue with an increase in mortality and morbidity. Here we report our modelled homo …
health issue with an increase in mortality and morbidity. Here we report our modelled homo …
Structural insights into coronavirus entry
MA Tortorici, D Veesler - Advances in virus research, 2019 - Elsevier
Coronaviruses (CoVs) have caused outbreaks of deadly pneumonia in humans since the
beginning of the 21st century. The severe acute respiratory syndrome coronavirus (SARS …
beginning of the 21st century. The severe acute respiratory syndrome coronavirus (SARS …
Structural basis for human coronavirus attachment to sialic acid receptors
Coronaviruses cause respiratory tract infections in humans and outbreaks of deadly
pneumonia worldwide. Infections are initiated by the transmembrane spike (S) glycoprotein …
pneumonia worldwide. Infections are initiated by the transmembrane spike (S) glycoprotein …
Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2
The trimeric SARS coronavirus (SARS-CoV) surface spike (S) glycoprotein consisting of
three S1-S2 heterodimers binds the cellular receptor angiotensin-converting enzyme 2 …
three S1-S2 heterodimers binds the cellular receptor angiotensin-converting enzyme 2 …
[HTML][HTML] Unexpected receptor functional mimicry elucidates activation of coronavirus fusion
Recent outbreaks of severe acute respiratory syndrome and Middle East respiratory
syndrome, along with the threat of a future coronavirus-mediated pandemic, underscore the …
syndrome, along with the threat of a future coronavirus-mediated pandemic, underscore the …
Stabilized coronavirus spikes are resistant to conformational changes induced by receptor recognition or proteolysis
Severe acute respiratory syndrome coronavirus (SARS-CoV) emerged in 2002 as a highly
transmissible pathogenic human betacoronavirus. The viral spike glycoprotein (S) utilizes …
transmissible pathogenic human betacoronavirus. The viral spike glycoprotein (S) utilizes …