[HTML][HTML] Mesenchymal stromal cells: putative microenvironmental modulators become cell therapy
M Krampera, K Le Blanc - Cell stem cell, 2021 - cell.com
An exceptional safety profile has been shown in a large number of cell therapy clinical trials
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …
that use mesenchymal stromal cells (MSCs). However, reliable potency assays are still …
[HTML][HTML] Mesenchymal stromal cells: clinical challenges and therapeutic opportunities
J Galipeau, L Sensébé - Cell stem cell, 2018 - cell.com
Mesenchymal stromal cells (MSCs) have been the subject of clinical trials for more than a
generation, and the outcomes of advanced clinical trials have fallen short of expectations …
generation, and the outcomes of advanced clinical trials have fallen short of expectations …
Global trends in clinical trials involving engineered biomaterials
M Lele, S Kapur, S Hargett, NM Sureshbabu… - Science …, 2024 - science.org
Engineered biomaterials are materials specifically designed to interact with biological
systems for biomedical applications. This paper offers the comprehensive analysis of global …
systems for biomedical applications. This paper offers the comprehensive analysis of global …
[HTML][HTML] Review of the current trends in clinical trials involving induced pluripotent stem cells
JY Kim, Y Nam, YA Rim, JH Ju - Stem cell reviews and reports, 2022 - Springer
In 2006, the induced pluripotent stem cell (iPSC) was presented to the world, paving the way
for the development of a magnitude of novel therapeutic alternatives, addressing a diverse …
for the development of a magnitude of novel therapeutic alternatives, addressing a diverse …
[HTML][HTML] Global trends in clinical trials involving pluripotent stem cells: a systematic multi-database analysis
J Deinsberger, D Reisinger, B Weber - NPJ Regenerative medicine, 2020 - nature.com
Pluripotent stem cells (PSCs) hold great potential for novel therapeutic approaches to
regenerate or replace functionally impaired tissues. Since the introduction of the induced …
regenerate or replace functionally impaired tissues. Since the introduction of the induced …
[HTML][HTML] ADSCs-derived extracellular vesicles alleviate neuronal damage, promote neurogenesis and rescue memory loss in mice with Alzheimer's disease
X Ma, M Huang, M Zheng, C Dai, Q Song… - Journal of Controlled …, 2020 - Elsevier
Despite the various mechanisms that involved in the pathogenesis of Alzheimer's disease
(AD), neuronal damage and synaptic dysfunction are the key events leading to cognition …
(AD), neuronal damage and synaptic dysfunction are the key events leading to cognition …
Concise review: a comprehensive analysis of reported adverse events in patients receiving unproven stem cell-based interventions
G Bauer, M Elsallab… - Stem cells translational …, 2018 - academic.oup.com
The promise of stem cell (SC) therapies to restore functions of damaged tissues and organs
brings enormous hope to patients, their families, loved ones, and caregivers. However, limits …
brings enormous hope to patients, their families, loved ones, and caregivers. However, limits …
[HTML][HTML] Multiplicity of mesenchymal stromal cells: finding the right route to therapy
A Wilson, M Hodgson-Garms, JE Frith… - Frontiers in …, 2019 - frontiersin.org
Over the last decade, the acceleration in the clinical use of mesenchymal stromal cells
(MSCs) has been nothing short of spectacular. Perhaps most surprising is how little we know …
(MSCs) has been nothing short of spectacular. Perhaps most surprising is how little we know …
[HTML][HTML] The impact of cryopreservation on bone marrow-derived mesenchymal stem cells: a systematic review
Mesenchymal stem cells (MSCs) represent an invaluable asset for the field of cell therapy.
Human Bone marrow-derived MSCs (hBM-MSCs) are one of the most commonly used cell …
Human Bone marrow-derived MSCs (hBM-MSCs) are one of the most commonly used cell …
Umbilical cord mesenchymal stromal cell transplantations: a systemic analysis of clinical trials
The advances and success of umbilical cord–derived mesenchymal stromal cells (UC-
MSCs) in experimental disease animal models have fueled the development of targeted …
MSCs) in experimental disease animal models have fueled the development of targeted …