Smart nanomaterials for cancer diagnosis and treatment
Innovations in nanomedicine has guided the improved outcomes for cancer diagnosis and
therapy. However, frequent use of nanomaterials remains challenging due to specific …
therapy. However, frequent use of nanomaterials remains challenging due to specific …
Overcoming challenges and limitations regarding the atomic force microscopy imaging and mechanical characterization of nanofibers
Atomic force microscopy (AFM) is a powerful tool that enables imaging and nanomechanical
properties characterization of biological materials. Nanofibers are the structural units of …
properties characterization of biological materials. Nanofibers are the structural units of …
Mapping viscoelastic properties of healthy and pathological red blood cells at the nanoscale level
In order to pass through the microcirculation, red blood cells (RBCs) need to undergo
extensive deformations and to recover the original shape. This extreme deformability is …
extensive deformations and to recover the original shape. This extreme deformability is …
Mechanical and structural comparison between primary tumor and lymph node metastasis cells in colorectal cancer
SW480 and SW620 colon carcinoma cell lines derive from primary tumour and lymph-node
metastasis of the same patient, respectively. For this reason, these cells represent an ideal …
metastasis of the same patient, respectively. For this reason, these cells represent an ideal …
Determining spatial variability of elastic properties for biological samples using AFM
Measuring the mechanical properties (ie, elasticity in terms of Young's modulus) of
biological samples using Atomic Force Microscopy (AFM) indentation at the nanoscale has …
biological samples using Atomic Force Microscopy (AFM) indentation at the nanoscale has …
Collagen is crucial target protein for scleral remodeling and biomechanical change in myopia progression and control
Y Sun, Y Sha, J Yang, H Fu, X Hou, Z Li, Y Xie, G Wang - Heliyon, 2024 - cell.com
In recent decades, the prevalence of myopia has been on the rise globally, attributed to
changes in living environments and lifestyles. This increase in myopia has become a …
changes in living environments and lifestyles. This increase in myopia has become a …
Atomic force microscopy nanoindentation method on collagen fibrils
SV Kontomaris, A Stylianou, A Malamou - Materials, 2022 - mdpi.com
Atomic Force Microscopy nanoindentation method is a powerful technique that can be used
for the nano-mechanical characterization of bio-samples. Significant scientific efforts have …
for the nano-mechanical characterization of bio-samples. Significant scientific efforts have …
Molecular mechanism responsible for fibronectin-controlled alterations in matrix stiffness in advanced chronic liver fibrogenesis
A Iwasaki, K Sakai, K Moriya, T Sasaki… - Journal of Biological …, 2016 - ASBMB
Fibrosis is characterized by extracellular matrix (ECM) remodeling and stiffening. However,
the functional contribution of tissue stiffening to noncancer pathogenesis remains largely …
the functional contribution of tissue stiffening to noncancer pathogenesis remains largely …
Molecular cues guiding matrix stiffness in liver fibrosis
T Saneyasu, R Akhtar, T Sakai - BioMed research international, 2016 - Wiley Online Library
Tissue and matrix stiffness affect cell properties during morphogenesis, cell growth,
differentiation, and migration and are altered in the tissue remodeling following injury and …
differentiation, and migration and are altered in the tissue remodeling following injury and …
Facile production of nanocomposites of carbon nanotubes and polycaprolactone with high aspect ratios with potential applications in drug delivery
E Niezabitowska, J Smith, MR Prestly, R Akhtar… - RSC …, 2018 - pubs.rsc.org
The geometries and surface properties of nanocarriers greatly influence the interaction
between nanomaterials and living cells. In this work we combine multiwalled carbon …
between nanomaterials and living cells. In this work we combine multiwalled carbon …