The prototypical xanthine oxidase (XO) inhibitor allopurinol, has been the cornerstone of the
clinical management of gout and conditions associated with hyperuricemia for several …

Nitric oxide (NO) is a gaseous signaling molecule that plays an important role in myriad
physiological processes including the regulation of vascular tone, neurotransmission …

Previous studies have demonstrated that skeletal muscles generate considerable reactive
oxygen during intense muscle contraction. However, the significance of this phenomenon …

Ischemia/reperfusion injury is often the final and irreversible factor causing flap failure in
microvascular surgery for head and neck defects. This paper begins with a detailed review …

In this study, we evaluated the abilities of a series of chalcones to inhibit the activity of the
enzyme xanthine oxidase (XO) and to scavenge radicals. 20 mono-and polyhydroxylated …

Respiratory muscle weakness resulting from both diaphragmatic contractile dysfunction and
atrophy has been hypothesized to contribute to the weaning difficulties associated with …

Les espèces chimiques oxygénées réactives dont font partie les radicaux libres sont le
résultat de réactions biochimiques souvent associées au métabolisme aérobie. Un …

We tested our hypothesis that postischemic conditioning (PostC) is effective in salvage of
ischemic skeletal muscle from reperfusion injury and the mechanism involves inhibition of …

The main aim of this new book is to summarise the knowledge on the metabolic
transformation of carnosine in excitable tissues of animals and human beings and to …

It is now recognized that respiratory muscle fatigue contributes to the development of
respiratory failure in some patients with lung disease. This observation has prompted an …