Background Critical examination of the quality and validity of available allergic rhinitis (AR)
literature is necessary to improve understanding and to appropriately translate this …

Genome wide association studies (GWASs) have revealed several airway disease-
associated risk loci. Their role in the onset of asthma, allergic rhinitis (AR) or chronic …

In recent years, evidence of the synergistic effects of pollen and viruses on respiratory health
has begun to accumulate. Pollen exposure is a known risk factor for the incidence and …

Allergic rhinitis, nonallergic rhinitis, and chronic rhinosinusitis are multifactorial upper airway
diseases with high prevalence. Several genetic and environmental factors are proposed to …

Background Pollen exposure induces local and systemic allergic immune responses in
sensitized individuals, but nonsensitized individuals also are exposed to pollen. The kinetics …

Allergic rhinitis, chronic rhinosinusitis, and asthma are highly prevalent, multifactorial chronic
airway diseases. Several environmental and genetic factors affect airway epithelial …

The objective of this review is to focus on putative modified epithelial functions related to
allergy. The dysregulation of the epithelial barrier might result in the allergen uptake, which …

The question what makes an allergen an allergen puzzled generations of researchers.
Pollen grains of anemophilous plants are the most important allergen carriers in ambient air …

The prevalence of allergic diseases such as allergic rhinitis is increasing, affecting up to
30% of the human population worldwide. Allergic sensitization arises from complex …

Airway allergen exposure induces inflammation among individuals with atopy that is
characterized by altered airway gene expression, elevated levels of T helper type 2 …