Eosinophils are important effector cells and therapeutic targets in allergic diseases.
Emerging data indicate that eosinophils infiltrate a variety of solid tumor types and have …

Immune checkpoint blockade (ICB) has heralded a new era in cancer therapy. Research
into the mechanisms underlying response to ICB has predominantly focused on T cells; …

Triple positive breast cancer (TPBC) is one of the most aggressive breast cancer. Due to the
unique cell phenotype, aggressiveness, metastatic potential and lack of receptors or targets …

Simple Summary Pancreatic cancer is a deadly disease with limited effective treatments.
Despite growing interest in immunotherapy for other cancer types, immunotherapy has not …

Gender differences in the functionality of the immune system have been attributed, in part, to
direct and indirect effects of sex steroids, especially estrogens, on immune cell repertoire …

Immune checkpoint inhibitors (ICIs) have revolutionized cancer therapy and now represent
the mainstay of treatment for many tumor types, including triple-negative breast cancer and …

This is a phase II study of PD-1 blockade plus chemoradiotherapy as preoperative therapy
for patients with locally advanced or borderline resectable pancreatic cancer (LAPC or …

Cancer cells circumvent immune surveillance via diverse strategies. In accordance, a large
number of complex studies of the immune system focusing on tumor cell recognition have …

Exploring the potential association between peripheral blood leukocyte counts and breast
cancer risk by Mendelian randomization (MR) analysis methods. Genetic data related to …

Dynamic changes in the blood-based biomarkers could be used as a prognostic biomarker
in patients treated with immune checkpoint inhibitors (ICIs), although the data are limited …